Sanjay Kumar
Banaras Hindu University
5 Papers
Sanjay Kumar is an academic researcher from Banaras Hindu University. The author has contributed to research in topics: Nociception & Chemistry. The author has an hindex of 3, co-authored 5 publications.
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Papers
Recent development in antihyperalgesic effect of phytochemicals: anti-inflammatory and neuro-modulatory actions
TL;DR: Compounds of high interest as potential antihyperalgesic agents are: curcumin, resveratrol, capsaicin, quercetin, eugenol, naringenin and epigallocatechin gallate (EGCG).
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Quercetin Ameliorates CFA-Induced Chronic Inflammatory Hyperalgesia via Modulation of ROS-Mediated ERK1/2 Signaling and Inhibition of Spinal Glial Activation In Vivo
Sanjay Kumar,Manjula Vinayak +1 more
TL;DR: It is suggested that repeated quercetin treatment is able to alleviate chronic inflammatory hyperalgesia by attenuating TNF-α-TNFR1–ERK1/2 signaling pathway via modulation of ROS and by suppression of central sensitization via inhibition of spinal glial activation.
7
ML171, a specific inhibitor of NOX1 attenuates formalin induced nociceptive sensitization by inhibition of ROS mediated ERK1/2 signaling.
TL;DR: The study for the first time depicts anti-nociceptive potential of ML171 via regulation of ROS mediated ERK1/2 signaling by inhibition of NOX1 activity in formalin induced inflammatory pain.
Plant-Microbe Symbiosis led synthesis of Bioactive Compounds
Pooja Kumari,Sanjay Kumar,Anupam Patra,Baljinder Singh,Vimal Pandey,Sahil Mehta +5 more
- 01 Jan 2021
TL;DR: Exploration and characterization of bacterial endophytes from diverse environment conditions producing novel bioactive compounds, have promising applications in medicine, agriculture, and veterinary sciences, enabling us to counter health challenges in ecofriendly manner.
NADPH oxidase1 inhibition leads to regression of central sensitization during formalin induced acute nociception via attenuation of ERK1/2-NFκB signaling and glial activation.
Sanjay Kumar,Manjula Vinayak +1 more
TL;DR: This is the first report demonstrating modulation of ERK1/2-NFκB signaling pathway, glial activation and regulation of neuron-glia crosstalk by NADPH oxidase1 inhibition towards its anti-nociceptive action.