Sang Hun Lee
Soonchunhyang University
135 Papers
407 Citations
Sang Hun Lee is an academic researcher from Soonchunhyang University. The author has contributed to research in topics: Mesenchymal stem cell & Apoptosis. The author has an hindex of 31, co-authored 124 publications. Previous affiliations of Sang Hun Lee include Pusan National University & Chonnam National University.
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Papers
Phloroglucinol inhibits the bioactivities of endothelial progenitor cells and suppresses tumor angiogenesis in LLC-tumor-bearing mice.
TL;DR: A novel role for phloroglucinol is suggested, which might be a modulator of circulating EPC bioactivities, eventually suppressing tumorigenesis and being a candidate compound for biosafe drugs that target tumor angiogenesis.
Inhibition of lewis lung cancer cell growth and migration by fucoidan
TL;DR: Findings identify the regulation of PI3K-Akt-mTOR signaling, MMP-2 expression, and caspase-3 activation by fucoidan as a critical anti-cancer mechanism in lung cancer cells, suggesting that fuco Aidan is a potential therapeutic agent for treating lung cancer.
Fucoidan Suppresses Mitochondrial Dysfunction and Cell Death against 1-Methyl-4-Phenylpyridinum-Induced Neuronal Cytotoxicity via Regulation of PGC-1α Expression
TL;DR: Investigation of the protective action of fucoidan against the detrimental action of 1-methyl-4-phenyl-pyridinium (MPP+), a neurotoxin used to model PD, in the mitochondria of SH-SY5Y neural cells suggests thatfucoidan could potentially be used as a therapeutic agent for PD.
Lnk is an important modulator of insulin-like growth factor-1/Akt/peroxisome proliferator-activated receptor-gamma axis during adipogenesis of mesenchymal stem cells
Jun Hee Lee,Sang Hun Lee,Hyang Seon Lee,Seung Taek Ji,Seok Yun Jung,Jae Ho Kim,Sun Sik Bae,Sang-Mo Kwon +7 more
TL;DR: Results suggested that Lnk adaptor protein regulated the adipogenesis of MSCs through the IGF-1/Akt/PPAR-γ pathway.
Protective Role of Fucoidan on Cisplatin-mediated ER Stress in Renal Proximal Tubule Epithelial Cells.
TL;DR: Fucoidan may be a potential adjuvant therapy for cancer patients treated with cisplatin as it preserves renal functionality and enhances the antioxidative capacity through up-regulation of PrPC.