Sandeep Kumar
7 Papers
Sandeep Kumar is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 5 publications.
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Papers
Age of Antibiotic Resistance in MDR/XDR Clinical Pathogen of Pseudomonas aeruginosa
Ashish Kothari,Radhika Sunil Kherdekar,Vishal Mago,Madhur Uniyal,G. Mamgain,Roop Bhushan Kalia,Sandeep Kumar,Neeraj Jain,Atul Pandey,Balram Ji Omar +9 more
TL;DR: The AMR mechanism considering the most common pathogen P. aeruginosa, its clinical impact, epidemiology, and save the authors' souls (SOS)-mediated resistance were highlighted and other therapeutic strategies, such as bacteriophage-based therapy and antimicrobial peptides, were described with clinical relevance.
10
Allergen-induced NLRP3/caspase1/IL-18 signaling initiate eosinophilic esophagitis and respective inhibitors protect disease pathogenesis
Chandrasekhar Yadavalli,Sathisha Upparahalli Venkateshaiah,Sandeep Kumar,Hemanth Kumar Kandikattu,Lokanatha Oruganti,C. Kathera,Anil Mishra +6 more
TL;DR: A stepwise mechanistic pathway of NLRP3/caspase1/IL-18-regulated immune responses operational in eosinophilic esophagitis is described, which depletes only IL-18-responsive pathogenic eosinophils, not naïve IL-5-generated eosinophils critical for maintaining innate immunity.
5
Proteomic Analysis of Female Synovial Fluid to Identify Novel Biomarkers for Osteoarthritis
P. R. Muller,Tae Jin Lee,Wenbo Zhi,Sandeep Kumar,Sagar S. Vyavahare,Ashok Sharma,Vikas Kumar,Carlos M. Isales,Monte Hunter,Sadanand Fulzele +9 more
TL;DR: In this paper , the authors identify differential protein content within the synovial fluid of female osteoarthritis and non-osteoarthritic (non-OA) patients.
Dietary interventions and molecular mechanisms for healthy musculoskeletal aging
Andrew Murphy,Sagar S. Vyavahare,Sandeep Kumar,Tae Jin Lee,Ashok Sharma,Satish Adusumilli,Mark W. Hamrick,Carlos M. Isales,Sadanand Fulzele +8 more
TL;DR: This study summarizes the literature on the nutritional protocols, emphasizing their impacts on bone and muscle biology, and identifies novel genes and signaling pathways involved in musculoskeletal biology.
Alterations in bone metabolites with age in C57BL/6 mice model
Dhara Patel,Tae Jin Lee,Sandeep Kumar,Sagar S. Vyavahare,Alison M. Worth,William D. Hill,Mark W. Hamrick,Carlos M. Isales,Rahul S. Shinde,Sadanand Fulzele +9 more
TL;DR: Age-related changes in bone tissue metabolites in C57BL/6 mice revealed that purine and D-glutamine and D -glutamate metabolism were significantly altered in both sexes, while arginine biosynthesis in females and lipid metabolism in males were highly affected.