Samson Mani
Cancer Institute
26 Papers
40 Citations
Samson Mani is an academic researcher from Cancer Institute. The author has contributed to research in topics: Epigenetics & Breast cancer. The author has an hindex of 8, co-authored 16 publications. Previous affiliations of Samson Mani include International Agency for Research on Cancer.
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Papers
Role of Circulating Cell-Free DNA in Cancers
TL;DR: This review summarizes the origin of cell-free DNA, recent advancements in the detection of Cell-Free DNA, a possible role in metastasis, and its importance as a non-invasive diagnostic assay for cancer.
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Identification of lncRNAs associated with early-stage breast cancer and their prognostic implications.
Arunagiri Kuha Deva Magendhra Rao,Krishna Patel,Suneetha Korivi Jyothiraj,Balaiah Meenakumari,Shirley Sundersingh,S. Velusami,Thangarajan Rajkumar,Akhilesh Pandey,Aditi Chatterjee,Harsha Gowda,Samson Mani +10 more
TL;DR: It is confirmed that the downregulation of ADAMTS9‐AS2 in breast cancer was due to promoter hypermethylation through in vitro silencing experiments and pyrosequencing, and the prognostic significance of DElncRNAs was evaluated based on TCGA datasets.
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Comprehensive Evaluation of Adherence to Therapy, Its Associations, and Its Implications in Patients With Chronic Myeloid Leukemia Receiving Imatinib
Radhika Unnikrishnan,Surendran Veeraiah,Samson Mani,Rejiv Rajendranath,Swaminathan Rajaraman,Grace Sahaya Vidhubala Elangovan,Venkatraman Radhakrishnan,Trivadi S. Ganesan,Tenali Gnana Sagar,Prasanth Ganesan +9 more
TL;DR: It is likely that increased long-term symptom burden due to side effects of imatinib could contribute to nonadherence, and interventions targeting individual components of QoL may improve adherence and outcomes in CML.
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DNA methylation changes associated with risk factors in tumors of the upper aerodigestive tract.
Samson Mani,Katarzyna Szymańska,Cyrille Cuenin,David Zaridze,Karen Balassiano,Sheila Coelho Soares Lima,Elena Matos,Alexander W. Daudt,Sergio Koifman,Victor Wünsch Filho,Ana M. B. Menezes,Maria Paula Curado,Gilles Ferro,Thomas Vaissière,Bakary S. Sylla,Massimo Tommasino,Luis Felipe Ribeiro Pinto,Paolo Boffetta,Pierre Hainaut,Paul Brennan,Zdenko Herceg +20 more
TL;DR: A high frequency of aberrant hypermethylation of several genes, including MYOD1, CHRNA3 and MTHFR in UADT tumors, is revealed and a potential mechanism by which environmental factors may deregulate key cellular genes involved in tumor suppression and contribute to UadT cancers is suggested.
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Targeted Resequencing of 30 Genes Improves the Detection of Deleterious Mutations in South Indian Women with Breast and/or Ovarian Cancers
TL;DR: The NGS platform is more sensitive and cost effective in detecting mutations in genes involved in hereditary breast and/or ovarian cancers and application of targeted resequencing of 30 genesinvolved in hereditary cancers is reported.
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