Sama Abdulmalik
University of Connecticut
12 Papers
3 Citations
Sama Abdulmalik is an academic researcher from University of Connecticut. The author has contributed to research in topics: Regeneration (biology) & Biology. The author has an hindex of 1, co-authored 4 publications. Previous affiliations of Sama Abdulmalik include University of Connecticut Health Center.
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Papers
Insulin immobilized PCL‐cellulose acetate micro‐nanostructured fibrous scaffolds for tendon tissue engineering
Daisy M. Ramos,Sama Abdulmalik,Michael R. Arul,Swetha Rudraiah,Cato T. Laurencin,Augustus D. Mazzocca,Sangamesh G. Kumbar +6 more
TL;DR: This work explores the use of insulin protein as a biochemical factor to aid in tendon healing and differentiation of cells on a biomimetic electrospun micro-nanostructured scaffold and finds a 75:25 ratio of PCL:CA was found to be optimal in promoting cellular attachment and insulin immobilization.
Stimuli-responsive peptide assemblies: Design, self-assembly, modulation, and biomedical applications
TL;DR: This comprehensive review provides detailed methodologies and advanced techniques on the synthesis of peptide nanomaterials from molecular biology, materials science, and nanotechnology, which will guide and inspire the molecular level design of peptides with specific and multiple functions for function-specific applications.
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Nanofiber matrix formulations for the delivery of Exendin-4 for tendon regeneration: In vitro and in vivo assessment
Sama Abdulmalik,Jack Gallo,John Nip,Sara Katebifar,Michael R. Arul,Amir Lebaschi,Lucas N. Munch,J. Bartly,Shilpa Choudhary,Ivo Kalajzic,Yeshavanth Kumar Banasavadi-Siddegowdae,Syam P. Nukavarapu,Sangamesh G. Kumbar +12 more
TL;DR: In this paper , a peptide growth factor (exendin-4; Ex-4) was used to enhance a nanofiber matrix in a tendon injury model to avoid burst release and protect the drug.
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The glucagon-like peptide 1 receptor agonist Exendin-4 induces tenogenesis in human mesenchymal stem cells.
Sama Abdulmalik,Daisy M. Ramos,Swetha Rudraiah,Yeshavanth Kumar Banasavadi-Siddegowda,Sangamesh G. Kumbar,Sangamesh G. Kumbar +5 more
TL;DR: In this article, the ability of the exendin-4 (Ex-4) peptide, a glucagon-like peptide 1 (GLP-1) receptor agonist, to induce tenocyte differentiation in bone marrow-derived human mesenchymal stem cells (hMSCs) was evaluated.
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Insulin-Functionalized Bioactive Fiber Matrices with Bone Marrow-Derived Stem Cells in Rat Achilles Tendon Regeneration.
Daisy M. Ramos,Sama Abdulmalik,Michael R. Arul,Naseem Sardashti,Yeshavanth Kumar Banasavadi-Siddegowda,Syam P. Nukavarapu,Hicham Drissi,Sangamesh G. Kumbar +7 more
TL;DR: The preliminary results establish the benefits of insulin-functionalized fiber matrices in promoting higher levels of collagen synthesis and alignment needed for functional recovery of tendon repair.
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