Sam Horrell
1 Papers
30 Citations
Sam Horrell is an academic researcher. The author has contributed to research in topics: Computer science. The author has an hindex of 1, co-authored 1 publications.
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Papers
COVID Moonshot: Open Science Discovery of SARS-CoV-2 Main Protease Inhibitors by Combining Crowdsourcing, High-Throughput Experiments, Computational Simulations, and Machine Learning
Hagit Achdout,A. Aimon,Elad Bar-David,Haim Barr,Amir Ben-Shmuel,Jim Bennett,Melissa L Bobby,Juliane Brun,Sarma Bvnbs,Mark Daniel Calmiano,Anna Carbery,Emma Cattermole,John D. Chodera,Austin Clyde,Joseph E. Coffland,Galit Cohen,Jason C. Cole,Alessandro Contini,Lisa Cox,Milan Cvitkovic,Alex Dias,Alice Douangamath,Shirly Duberstein,Tim Dudgeon,Louise Dunnett,Peter K. Eastman,Noam Erez,Michael Fairhead,D. Fearon,Oleg Fedorov,Matteo P. Ferla,Holly Foster,Richard Foster,Ronen Gabizon,P. Gehrtz,Carina Gileadi,Charline Giroud,William G. Glass,Robert C. Glen,Itai Glinert,Marian V. Gorichko,T.J. Gorrie-Stone,Edward J Griffen,Jag Paul Heer,Michelle L. Hill,Sam Horrell,Matthew F. D. Hurley,Tomer Israely,Andrew Jajack,Eric Jnoff,Tobias John,Anastassia L. Kantsadi,Peter W. Kenny,J. L. Kiappes,Lizbe Koekemoer,Boris Kovar,T. Krojer,Alpha A. Lee,Bruce A. Lefker,Haim Levy,Nir London,Petra Lukacik,Hannah E. Bruce Macdonald,Beth MacLean,Tika R. Malla,Tatiana Matviiuk,Willam McCorkindale,Sharon Melamed,Oleg M. Michurin,Halina Mikolajek,Aaron Morris,Garrett M. Morris,Melody Jane Morwitzer,Demetri Moustakas,Jose Brandao Neto,Vladas Oleinikovas,Gijs J. Overheul,David Owen,Ruby Pai,Jin Pan,Nir Paran,Benjamin Ian Perry,Maneesh Pingle,Jakir Pinjari,Boaz Politi,Ailsa Powell,Vladimir Psenak,Reut Puni,Victor L. Rangel,Rambabu N. Reddi,St Patrick Reid,Efrat Resnick,Matthew C. Robinson,Ralph P. Robinson,Dominic Rufa,Christopher J. Schofield,Aarif Shaikh,Jiye Shi,Khriesto A. Shurrush,Assa Sittner,R. Skyner,Adam Smalley,Mihaela D. Smilova,John Spencer,Claire Strain-Damerell,Vishwanath Swamy,Hadas Tamir,Rachael Tennant,Andrew Thompson,Warren Thompson,Susana Tomasio,Anthony Tumber,Ioannis Vakonakis,Ronald P. van Rij,Finny S. Varghese,Mariana Vaschetto,Einat B. Vitner,Vincent A. Voelz,Annette von Delft,Frank von Delft,Martin Walsh,Walter Ward,Charlie Weatherall,Shay Weiss,Conor Francis Wild,Matthew Wittmann,Nathan Wright,Yfat Yahalom-Ronen,Daniel Zaidmann,Hadeer Zidane,Nicole Zitzmann +130 more
TL;DR: This manuscript describes the methodologies leading to both covalent and non-covalent inhibitors displaying protease IC50 values under 150 nM and viral inhibition under 5 uM in multiple different viral replication assays.