8 Papers
20 Citations
Sai Chen is an academic researcher from Third Military Medical University. The author has contributed to research in topics: Medicine & Anesthesia. The author has an hindex of 2, co-authored 3 publications.
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Papers
Effect of Intraoperative Esketamine Infusion on Postoperative Sleep Disturbance After Gynecological Laparoscopy
TL;DR: In this paper , the effect of intraoperative esketamine infusion on incidence of sleep disturbance following gynecological laparoscopic surgery was examined in a randomized clinical trial, and the results showed that the infusion improved sleep quality.
Re-enforcing hypoxia-induced polyploid cardiomyocytes enter cytokinesis through activation of β-catenin
TL;DR: It is shown that β-catenin, a key regulator in heart development, can increase cytokinesis in polyploid multinucleated CMs via upregulation of ECT2, which suggests a potential field ofpolyploid CM research that may be exploitable for cardiac regeneration therapy.
Mechanical ventilation induces lung and brain injury through ATP production, P2Y1 receptor activation and dopamine release
Wei Wei,Zhen-Tao Sun,Shifeng He,Wan-Li Zhang,Sai Chen,Yanjie Cao,Niping Wang +6 more
TL;DR: It is elicited that lung injury induced by mechanical ventilation exacerbated brain injury in mice by increasing ATP production, activating the P2Y1 receptor, and thus promoting DA release.
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Risk Factors for Permanent Neurological Dysfunction and Early Mortality in Patients with Type A Aortic Dissection Requiring Total Arch Replacement.
TL;DR: Hypertension was independently associated with postoperative PND, and age and postoperativePND were predictors for early mortality in patients who underwent total arch replacement and stented elephant trunk implantation in the descending aorta.
Gut microbiota-mediated metabolic restructuring aggravates emotional deficits after anesthesia/surgery in rats with preoperative stress
TL;DR: It was found that anesthesia/surgery aggravated anxiety-like and depression-like behaviors in rats under preoperative stress, and abnormalities in the gut microbiota contribute to postoperative metabolic restructuring, neuroinflammation, and psychiatric deficits in Rats under preoper stress.
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