Saddek Mohand-Said
Vision Institute
155 Papers
1.1K Citations
Saddek Mohand-Said is an academic researcher from Vision Institute. The author has contributed to research in topics: Retinitis pigmentosa & Retinal. The author has an hindex of 38, co-authored 145 publications. Previous affiliations of Saddek Mohand-Said include Quinze-Vingts National Eye Hospital & Pierre-and-Marie-Curie University.
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Papers
Functional rescue of cone photoreceptors in retinitis pigmentosa.
José-Alain Sahel,Thierry Léveillard,Thierry Léveillard,Serge Picaud,Serge Picaud,Deniz Dalkara,Deniz Dalkara,Katia Marazova,Katia Marazova,Avinoam B. Safran,Michel Paques,Jens Duebel,Jens Duebel,Botond Roska,Saddek Mohand-Said +14 more
TL;DR: There is no known effective treatment that can prevent or reverse the vision loss in RP, and pathologies that affect the photoreceptor structure and function result in impaired vision.
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•Journal Article
A novel DFNB31 mutation associated with Usher type 2 syndrome showing variable degrees of auditory loss in a consanguineous Portuguese family.
Isabelle Audo,Kinga M. Bujakowska,Saddek Mohand-Said,Sophie Tronche,Marie-Elise Lancelot,Aline Antonio,Aurore Germain,Christine Lonjou,Wassila Carpentier,José-Alain Sahel,Shomi S. Bhattacharya,Christina Zeitz +11 more
TL;DR: A novel truncating mutation in DFNB31 is reported associated with severe rod-cone dystrophy and varying degrees of hearing impairment in a consanguineous family of Portuguese origin.
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Intravitreal Injection of Ganglioside GM1 After Ischemia Reduces Retinal Damage in Rats
TL;DR: GM1 protects the rat retina from pressure-induced ischemic injury when given intravitreally after the insult, and could be of therapeutic interest.
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Phenotypic characteristics of rod-cone dystrophy associated with myo7a mutations in a large french cohort.
Samer Khateb,Samer Khateb,Samer Khateb,Saddek Mohand-Said,Saddek Mohand-Said,Marco Nassisi,Marco Nassisi,Crystel Bonnet,Anne-Françoise Roux,Camille Andrieu,Aline Antonio,Aline Antonio,Christel Condroyer,Christina Zeitz,Céline Devisme,Natalie Loundon,Sandrine Marlin,Christine Petit,Bahram Bodaghi,José-Alain Sahel,Isabelle Audo,Isabelle Audo,Isabelle Audo +22 more
TL;DR: Functional visual characteristics of this subset of patients followed a linear decline as in other typical rod-cone dystrophy, but structural changes were variable indicating the need for a case-by-case evaluation for prognostic prediction and choice of potential therapies.
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