S. Wells
University of Birmingham
8 Papers
S. Wells is an academic researcher from University of Birmingham. The author has contributed to research in topics: Medicine & Computer science. The author has an hindex of 4, co-authored 4 publications. Previous affiliations of S. Wells include University of Melbourne.
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Papers
Epicardial Adipose Tissue Accumulation Confers Atrial Conduction Abnormality.
Chrishan J. Nalliah,Jimmy D. Bell,Antonia J.A. Raaijmakers,Helen M. Waddell,S. Wells,Gabriel B. Bernasochi,Magdalene K. Montgomery,Simon Binny,Troy Watts,Subodh B Joshi,Elaine Lui,Choon Boon Sim,Marco Larobina,Michael O’Keefe,John Goldblatt,Alistair Royse,Geoffrey Lee,Enzo R. Porrello,Matthew J. Watt,Peter M. Kistler,Prashanthan Sanders,Lea M.D. Delbridge,Jonathan M. Kalman,Jonathan M. Kalman +23 more
TL;DR: Findings indicate that atrial pathophysiology is critically dependent on local EpAT accumulation and infiltration, and this effect can be attributed to an EpAT-cardiomyocyte paracrine axis.
161
ElectroMap: High-throughput open-source software for analysis and mapping of cardiac electrophysiology
Christopher O’Shea,Andrew P. Holmes,Ting Y. Yu,James Winter,S. Wells,S. Wells,Joao Correia,Bastiaan J. Boukens,Joris R. de Groot,Gavin S Chu,Gavin S Chu,Xin Li,G. André Ng,G. André Ng,Paulus Kirchhof,Larissa Fabritz,Kashif Rajpoot,Davor Pavlovic +17 more
TL;DR: ElectroMap is presented, an adaptable, high-throughput, open-source software for processing, analysis and mapping of complex electrophysiology datasets from diverse experimental models and acquisition modalities, employing multiple methodologies currently not widely available to researchers.
86
High resolution optical mapping of cardiac electrophysiology in pre-clinical models
Christopher O’Shea,James Winter,S. Nashitha Kabir,Molly O’Reilly,S. Wells,Olivia Baines,L C Sommerfeld,Joao Correia,M. Lei,Paulus Kirchhof,Andrew B. Holmes,Larissa Fabritz,Kashif Rajpoot,Davor Pavlovic +13 more
TL;DR: In this article , the authors have generated a comprehensive post-processed dataset characterising the baseline cardiac electrophysiology in these widely used pre-clinical models, providing reference information detailing the effect of heart rate, clinically used antiarrhythmic drugs, ischaemia-reperfusion and sympathetic nervous stimulation.
High resolution optical mapping of cardiac electrophysiology in pre-clinical models
Christopher O’Shea,James Winter,S. Nashitha Kabir,Molly O’Reilly,S. Wells,Olivia Baines,L C Sommerfeld,Joao Correia,M. Lei,Paulus Kirchhof,Andrew B. Holmes,Larissa Fabritz,Kashif Rajpoot,Davor Pavlovic +13 more
TL;DR: In this paper , the authors have generated a comprehensive post-processed dataset characterising the baseline cardiac electrophysiology in these widely used pre-clinical models, providing reference information detailing the effect of heart rate, clinically used antiarrhythmic drugs, ischaemia-reperfusion and sympathetic nervous stimulation.
Greater Cardiac Adiposity is Associated With Diastolic Dysfunction and Cardiomyocyte Lipid Accumulation in Rodents
TL;DR: In this article , the authors assess the mechanistic relationship between cardiac adiposity and diastolic dysfunction in mice and rats, and find that obesity is an independent risk factor for the development of diastingolic dysfunction and associated with marked pericardial adipose tissue accumulation.