20 Papers
254 Citations
S. Tracy is an academic researcher from University of Nebraska Medical Center. The author has contributed to research in topics: Viral replication & Virus. The author has an hindex of 13, co-authored 20 publications.
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Papers
Replication of Coxsackievirus B3 in Primary Cell Cultures Generates Novel Viral Genome Deletions
TL;DR: Coxsackievirus B3 generates 5′-terminally deleted genomes (TDs) during replication in murine hearts and it is shown that CVB3 populations with TDs can also be generated within two to three passages ofCVB3 in primary, but not immortalized, cell cultures.
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Evolution of Virulence in Picornaviruses
TL;DR: The Picornaviridae encompass many positive-strand RNA viruses, all of which share a generally similar genome design and capsid structure, but which induce quite diverse diseases in humans and other animals.
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Characterization of an infectious cDNA copy of the genome of a naturally occurring, avirulent coxsackievirus B3 clinical isolate.
TL;DR: This is the first report characterizing a cloned CVB3 genome from an avirulent strain, and inoculation of mice withCVB3/GA protected mice completely against myocarditis and pancreatitis induced by cardiovirulent CVB 3 challenge.
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Genetics of coxsackievirus virulence.
TL;DR: Based on molecular detection data, these data indicate that there are at least 5000 or more occurrences of enterovirus-induced DCM alone per year in the United States.
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Generation of an infectious cDNA of a highly cardiovirulent coxsackievirus B3(CVB3m) and comparison to other infectious CVB3 cDNAs
TL;DR: P phenotypic diversity of CVB3 within the prototype Nancy strain is an example of RNA viruses adapting to changing environments (cells, mice and humans) through mutations and selective pressure.
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