S Ohzeki
6 Papers
287 Citations
S Ohzeki is an academic researcher. The author has contributed to research in topics: Antigen & Cytotoxic T cell. The author has an hindex of 6, co-authored 6 publications.
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Papers
•Journal Article
Cyclosporin A does not prevent expression of Tac antigen, a probable TCGF receptor molecule, on mitogen-stimulated human T cells.
TL;DR: Evidence is presented that CsA might not prevent the expression of probable functional receptor sites for TCGF in mitogen-dependent activation of human T cells, and the functional properties of activated T cells might be correlated with their ability to express Tac antigen.
105
•Journal Article
Functional significance of Tac antigen expressed on activated human T lymphocytes: Tac antigen interacts with T cell growth factor in cellular proliferation.
TL;DR: Observations suggested that anti-Tac antibody might specifically block the binding of TCGF to the corresponding membrane binding sites, resulting in the inhibition ofTCGF-dependent proliferation of CTC.
85
•Journal Article
Sequential expression of T cell activation (Tac) antigen and Ia determinants on circulating human T cells after immunization with tetanus toxoid.
TL;DR: It is shown that an increase in circulating T cells expressing Tac antigen as well as Ia determinants occurred in normal individuals after immunization with tetanus toxoid, and the fact that induction of Tac-positive and Ia-positive T cells might occur at different stages of T cell activation and in different subsets of T cells seemed to be important for elucidating their roles in the in vivo T cell proliferation and differentiation.
81
•Journal Article
Immunohistologic localization and immune phenotypes of lymphocytes expressing Tac antigen in human lymphoid tissues.
TL;DR: It was found that a substantial number of lymphoid cells reactive with anti-Tac antibody were present in these tissues, implying the plausible notion that an IL 2-mediated immune activation of T cells may actually occur in local lymphoid organs.
34
•Journal Article
Kinetics of expression of T-cell "activation" antigens on in vivo- and in vitro-stimulated T cells.
TL;DR: The in vivo expression of T-cell activation antigens defined by means of an OKT series of monoclonal antibodies and the anti-Tac antibody was evaluated in peripheral T lymphocytes obtained from patients with infectious mononucleosis and in cerebrospinal fluid cells collected from individuals with mumps meningitis by the immunoperoxidase method.
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