S. Oddera
Istituto Giannina Gaslini
10 Papers
109 Citations
S. Oddera is an academic researcher from Istituto Giannina Gaslini. The author has contributed to research in topics: Bronchoalveolar lavage & Eosinophil. The author has an hindex of 5, co-authored 10 publications.
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Papers
Airway eosinophilic inflammation and bronchial hyperresponsiveness after allergen inhalation challenge in asthma.
TL;DR: In stable asthmatic patients an ongoing activation of eosinophils parallels their migration, but this eos inophilic inflammation is not strictly related to bronchial reactivity to Mch, and eosInophil inflammation may be partially associated with the degree of airway hyperresponsiveness.
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β2-agonist-induced inhibition of neutrophil chemotaxis is not associated with modification of LFA-1 and Mac-1 expression or with impairment of polymorphonuclear leukocyte antibacterial activity
TL;DR: The results suggest that short-acting beta 2-adrenoceptor agonists, such as fenoterol, are able partially to reduce neutrophil recruitment in the airways without interfering with the processes involved in phagocytic activity against bacteria.
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Bronchial and Bronchoalveolar Inflammation in Single Early and Dual Responders after Allergen Inhalation Challenge
TL;DR: The development of LAR after allergen inhalation challenge is associated with an early recruitment of eosinophils and with epithelial desquamation in the airways, independently of the type of bronchial response.
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Expression of cytokine mRNA in bronchoalveolar lavage cells from atopic asthmatics before late antigen-induced reaction.
Antonio Miadonna,S. Gibelli,Maurizio Lorini,Alberto Tedeschi,S. Oddera,Giovanni A. Rossi,Emanuele Crimi +6 more
TL;DR: The cellular environment in BAL fluids from allergic asthmatics before the clinical appearance of the late airway reaction shows an unrestricted expression of mRNA for cytokines, suggesting the local cytokine milieu could have an important role in the modulation of bronchial inflammation and in the appearance of allergic symptoms.
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Budesonide down-regulates eosinophil locomotion but has no effects on ECP release or on H2O2 production.
Sabina Lantero,S. Oddera,Michela Silvestri,R. Gonzalez Rodriguez,M. C. Morelli,Giovanni A. Rossi +5 more
TL;DR: Concentrations of budesonide similar to those obtained in vivo are effective in inhibiting eosinophil locomotion but not in down-regulating the release of reactive oxygen species and granule-associated proteins.
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