S Koike
Iwate Medical University
5 Papers
102 Citations
S Koike is an academic researcher from Iwate Medical University. The author has contributed to research in topics: Septic shock & Sepsis. The author has an hindex of 3, co-authored 5 publications.
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Papers
•Journal Article
Levels of soluble adhesion molecules and cytokines in patients with septic multiple organ failure
Shigeatsu Endo,Katsuya Inada,T Kasai,Tetsuya Takakuwa,Yamada Y,S Koike,Go Wakabayashi,Niimi M,Taniguchi S,Masao Yoshida +9 more
TL;DR: Investigation of plasma levels of inflammatory cytokine activating neutrophils, soluble adhesive molecules, and endotoxin found that endotoxin and inflammatory cytokines damage vascular endothelium as well as various other cells and produce, a large number of adhesion molecule, especially in patients with septic MOF, causing leakage ofAdhesion molecules into blood.
73
•Journal Article
Functional modification of vascular endothelial cells by cytokines during septic shock.
Shigeatsu Endo,Katsuya Inada,Y Yamada,Tetsuya Takakuwa,Hajime Nakae,T Kasai,S Koike,Yoshihiro Inoue,Niimi M,Go Wakabayashi,Taniguchi S +10 more
TL;DR: In serious diseases such as septic shock, the vascular endothelial constricting factors, endothelin and TXB2, and the blood vessel relaxing factors NOx and PGF1 alpha increase almost simultaneously, which suggests that the body's regulating mechanisms are disrupted in these serious conditions.
18
•Journal Article
Nuclear matrix protein, tumor necrosis factor-alpha, and nitrite/nitrate levels in patients with multiple organ dysfunction syndrome.
Y Yamada,Shigeatsu Endo,T Kasai,S Koike,Tetsuya Takakuwa,Yoshihiro Inoue,Niimi M,Endo Y,Go Wakabayashi,Katsuya Inada +9 more
TL;DR: It is suggested that apoptosis can occur in the presence of MODS, and that its extent increases as the number of failing organs increases, and TNF-alpha and NO are involved in the induction of apoptosis.
10
•Journal Article
The effect of ulinastatin on CFU-C colony formation in mouse myelocyte cultures.
Shigeatsu Endo,Katsuya Inada,T Kasai,S Koike,Y Kamei,Y Yamada,Go Wakabayashi,Masao Yoshida,Y Yanagiya +8 more
TL;DR: Ulinastatin was found to increase the number of colony forming units of mouse myelocytes in culture, suggesting that it might promote hematopoiesis.
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