9 Papers
51 Citations
S. Jham is an academic researcher from Queen Elizabeth Hospital Birmingham. The author has contributed to research in topics: Transplantation & Antigen. The author has an hindex of 7, co-authored 9 publications. Previous affiliations of S. Jham include University Hospitals Birmingham NHS Foundation Trust & University of Birmingham.
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Papers
Transitional B Lymphocytes Are Associated With Protection From Kidney Allograft Rejection: A Prospective Study
Shazia Shabir,J. Girdlestone,David Briggs,Baksho Kaul,Helen Smith,Sunil Daga,Sourabh Chand,S. Jham,C. Navarrete,Lorraine Harper,Simon Ball,Richard Borrows +11 more
TL;DR: The potential relevance of transitional (“regulatory”) B cells as a biomarker and therapeutic intervention in transplantation is supported, and relationships between humoral immunity, cellular immunity and nonadherence are highlighted.
111
Validity of glycated haemoglobin to diagnose new onset diabetes after transplantation.
TL;DR: HbA1c (≥6.5%) can be utilized to diagnose NODAT beyond 3 months post‐transplantation but the OGTT remains the gold‐standard tool.
71
Assessing and Comparing Rival Definitions of Delayed Renal Allograft Function for Predicting Subsequent Graft Failure
Jason Moore,Shazia Shabir,Sourabh Chand,Andrew Bentall,Andrew McClean,Winnie Chan,S. Jham,David Benavente,Adnan Sharif,Simon Ball,Paul Cockwell,Richard Borrows +11 more
TL;DR: This study confirms the utility of fDGF as an early marker of subsequent inferior allograft outcomes, suggesting superiority over the traditional (often subjective) dialysis-based definition of DGF.
42
Impaired Direct Priming of CD8 T Cells by Donor-Derived Cytomegalovirus Following Kidney Transplantation
Shazia Shabir,Baksho Kaul,Annette Pachnio,Gemma D. Banham,Gemma D. Banham,Helen Smith,Sourabh Chand,Sourabh Chand,S. Jham,S. Jham,Lorraine Harper,Simon Ball,Simon Ball,Afsar Rahbar,Cecilia Söderberg-Nauclér,Paul Moss,Richard Borrows,Richard Borrows +17 more
TL;DR: No recipients mounted responses to CMV presented by donor-specific HLA, despite the detection of CMV antigen expression in all seropositive donor organs examined, suggesting that the allograft of Class I HLA-mismatched seropOSitive donors is inaccessible to CD8+ T cell responses.
Increased incidence of infections following the late introduction of mycophenolate mofetil in renal transplant recipients
Rajesh Hanvesakul,Chandrashekhar A. Kubal,S. Jham,Esha Sarkar,Kevin S. Eardley,Dwomoa Adu,Paul Cockwell +6 more
TL;DR: There is significant morbidity associated with an increased incidence of infection after late introduction of MMF at standard doses in renal transplant recipients and this risk may be related to GFR at the time of conversion.