S.J. Bailey
University of Surrey
9 Papers
265 Citations
S.J. Bailey is an academic researcher from University of Surrey. The author has contributed to research in topics: Adenosine & Suramin. The author has an hindex of 8, co-authored 9 publications.
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Papers
A study of the purinoceptors mediating contraction in the rat colon.
S.J. Bailey,Susanna M.O. Hourani +1 more
TL;DR: The results are consistent with the existence in the rat colon muscularis mucosae of a mixed population of purine receptors of P2Y and P1 types and suggest that its action in this tissue is mediated by P1‐purinoceptors, although 8‐SPT was more potent here than has previously been demonstrated.
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Characterization of the P1-purinoceptors mediating contraction of the rat colon muscularis mucosae.
TL;DR: The results indicate that the P1‐purinoceptor mediating contraction is of the A1 subtype, as has been found in other tissues in which adenosine causes contraction, and confirms the finding that the stable ATP analogue, AMPPCP, has an unexpected direct action on these A1 receptors.
Effects of purines on the longitudinal muscle of the rat colon.
S.J. Bailey,Susanna M.O. Hourani +1 more
TL;DR: ATP and AMPPCP appear to be acting on the A2 receptors in this tissue largely via their degradation product adenosine.
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Differential effects of suramin on P2‐purinoceptors mediating contraction of the guinea‐pig vas deferens and urinary bladder
S.J. Bailey,Susanna M.O. Hourani +1 more
TL;DR: The effect of the P2‐purinoceptor antagonist, suramin, was investigated on contractions of the guinea‐pig vas deferens and urinary bladder induced by adenosine 5′‐triphosphate (ATP) and by the other naturally occurring nucleoside triphosphates, although maximal responses to these agonists were not achieved in either tissue.
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Direct effects of adenylyl 5′‐(β,γ‐methylene)diphosphonate, a stable ATP analogue, on relaxant P1‐purinoceptors in smooth muscle
TL;DR: AMPPCP has pronounced but variable agonist actions on P1‐purinoceptors, and appears to act entirely via these receptors on the rat duodenum although in the guinea‐pig taenia caeci this action is less important and it acts largely via P2Y‐purinosceptors.
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