Malignant mesothelioma is an insidious neoplasm arising from the mesotelial surfaces, of the pleural and peritoneal cavities, the tunica vaginalis, or the pericardium. The predominant cause is inhalation exposure to asbestos. We present a rare case of primary malignant mesothelioma of the peritoneum in a 64 year old man without history of inhalation exposure to asbestos. The initial symptoms were constitutional syndrome and right pleural effusion. Positron emission tomography combined with computed tomography (PET/TC) was useful for a supporting diagnosis and to determine the extension. The patient received treatment with systemic palliative chemotherapy, cisplatin-pemetrexed. After three cycles, partial response was observed, but the evolution was fatal due to secondary toxicity of chemotherapy.

/pdf/mesotelioma-peritoneal-una-presentacion-clinica-inusual-en-3gz6vwv4y3.pdf

Mesotelioma peritoneal: una presentación clínica inusual en un paciente sin exposición al asbesto

Probióticos en síndrome de intestino irritable

Open-label study of pemetrexed alone or in combination with cisplatin for the treatment of patients with peritoneal mesothelioma: outcomes of an expanded access program.

4132 Background: Primary peritoneal mesothelioma is a rare disease with an unpredictable clinical course. This has led to a variety of treatment options, ranging from minimal debulking, debulking with adjuvant intraperitoneal (i.p.) chemotherapy to aggressive debulking with peritonectomy with hyperthermic intra-operative i.p. perfusion. It is unclear whether outcome is dependent on treatment, patient selection or tumor biology. Methods: A retrospective review of all patients with primary peritoneal mesothelioma treated at a single institution between 1/1/82–1/1/02 was performed. Patient, tumor and treatment variables were reviewed. Results: Thirty-seven pts. with primary peritoneal mesothelioma were identified. Patients with pleural mesothelioma with peritoneal extension were excluded. Median follow-up was 49 months (range 3–97mos.) There were 15 male and 22 female pts. with a median age of 56 years. All pts. were explored with the pre-operative goal of maximal cytoreduction with minimal sacrifice of adja...

Primary peritoneal mesothelioma: How aggressive should we be?

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Primary peritoneal mesothelioma: How aggressive should we be?