S Franck
University of Mainz
6 Papers
2 Citations
S Franck is an academic researcher from University of Mainz. The author has contributed to research in topics: Experimental autoimmune encephalomyelitis & Antigen. The author has an hindex of 3, co-authored 6 publications.
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Papers
Application of patient‐derived liver cancer cells for phenotypic characterization and therapeutic target identification
D Castven,D Becker,Carolin Czauderna,Diana Wilhelm,Jesper B. Andersen,Susanne Strand,Monika Hartmann,Stefanie Heilmann-Heimbach,Wilfried Roth,N Hartmann,Beate K. Straub,F Mahn,S Franck,S Pereira,A Haupts,Arndt Vogel,Marcus A. Wörns,Arndt Weinmann,Stefan Heinrich,Hauke Lang,Snorri S. Thorgeirsson,Peter R. Galle,Jens U. Marquardt +22 more
TL;DR: Integrative genomic and transcriptomic approaches demonstrated that PDCL more closely resemble molecular and prognostic features of PLC than established cell lines and are valuable tool for direct target evaluation.
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Dendritic cells tip the balance towards induction of regulatory T cells upon priming in experimental autoimmune encephalomyelitis.
Magdalena Paterka,Jan Oliver Voss,Johannes Werr,Eva Reuter,S Franck,Tina Leuenberger,Josephine Herz,Helena Radbruch,Tobias Bopp,Volker Siffrin,Frauke Zipp +10 more
TL;DR: It is demonstrated that conditional ablation of DCs during the priming phase of myelin-specific T cells in experimental autoimmune encephalomyelitis (EAE) selectively aborts inducible Treg (iTreg) induction, whereas generation of T helper (Th)1/17 cells is unaltered.
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Application of patient derived liver cancer cell lines for phenotypic characterization and therapeutic target identification
D Castven,D Becker,Carolin Czauderna,D Wilhelm,Jesper B. Andersen,Susanne Strand,Monika Hartmann,Stefanie Heilmann-Heimbach,R Wilfried,N Hartmann,Beate K. Straub,F Mahn,S Franck,S Pereira,A Haupts,Arndt Vogel,MA Wörns,Arndt Weinmann,Stefan Heinrich,Hauke Lang,Snorri S. Thorgeirsson,Peter R. Galle,Jens U. Marquardt +22 more
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Phenotype of Antigen Unexperienced TH Cells in the Inflamed Central Nervous System in Experimental Autoimmune Encephalomyelitis.
TL;DR: Using flow cytometric analyses of central nervous system-derived lymphocytes, it was found that only antigen-specific, formerly naive T helper cells became activated during inflammation of thecentral nervous system encountering their corresponding antigen.