3 Papers
54 Citations
S E Burk is an academic researcher from University of Cincinnati Academic Health Center. The author has contributed to research in topics: Gene expression & Alternative splicing. The author has an hindex of 3, co-authored 3 publications.
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Papers
Structure of the rat plasma membrane Ca(2+)-ATPase isoform 3 gene and characterization of alternative splicing and transcription products. Skeletal muscle-specific splicing results in a plasma membrane Ca(2+)-ATPase with a novel calmodulin-binding domain.
S E Burk,Gary E. Shull +1 more
TL;DR: The rat gene encoding isoform 3 of the plasma membrane Ca(2+)-ATPase (PMCA3) is isolated and its exon/intron organization is determined and a 42-nucleotide exon (exon 8) that is included in the skeletal muscle PMCA3 m RNAs, but may be either included or excluded in the brain mRNAs is identified.
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cDNA cloning, functional expression, and mRNA tissue distribution of a third organellar Ca2+ pump.
TL;DR: The characterization of a rat kidney cDNA that encodes a novel Ca2+-transporting ATPase and that its mRNA is expressed in a broad variety of both muscle and non-muscle tissues are described.
Alternative splicing of exons encoding the calmodulin-binding domains and C termini of plasma membrane Ca(2+)-ATPase isoforms 1, 2, 3, and 4.
TL;DR: Rat plasma membrane Ca(2+)-ATPase (PMCA) mRNAs were examined by S1 nuclease protection and polymerase chain reaction and the corresponding genes were analyzed to determine the tissue-specific splicing patterns involving exons encoding the calmodulin-binding domains and C termini.