Nonrigid registration of dynamic medical imaging data using nD + t B-splines and a groupwise optimization approach.

The presented study details the virtual deployment of a bifurcated stent graft (Medtronic Talent) in an Abdominal Aortic Aneurysm model, using the finite element method. The entire deployment procedure is modeled, with the stent graft being crimped and bent according to the vessel geometry, and subsequently released. The finite element results are validated in vitro with placement of the device in a silicone mock aneurysm, using high resolution CT scans to evaluate the result. The presented work confirms the capability of finite element computer simulations to predict the deformed configuration after endovascular aneurysm repair (EVAR). These simulations can be used to quantify mechanical parameters, such as neck dilations, radial forces and stresses in the device, that are difficult or impossible to obtain from medical imaging.

Virtual evaluation of stent graft deployment: A validated modeling and simulation study☆

Dynamics of the aorta before and after endovascular aneurysm repair: a systematic review.

With advancements in technology and a better understanding of human cardiovascular physiology, research as well as clinical care can go beyond dimensional anatomy offered by traditional imaging and investigate aortic functional properties and the impact disease has on this function. Linking the knowledge of the histopathological changes with the alterations in aortic function observed on noninvasive imaging results in a better understanding of disease pathophysiology. Translating this to clinical medicine, these noninvasive imaging assessments of aortic function are proving to be able to diagnose disease, better predict risk, and assess response to therapies. This review is designed to summarize the various hemodynamic measures that can characterize the aorta, the various noninvasive techniques, and applications for various disease states.

Noninvasive Imaging of Flow and Vascular Function in Disease of the Aorta.

Patient-specific biomechanical profiling in abdominal aortic aneurysm development and rupture

Quantification of aortic distensibility in abdominal aortic aneurysm using ECG-gated

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Quantification of aortic distensibility in abdominal aortic aneurysm using ECG-gated