Ryuichi Morishita
Osaka University
708 Papers
8.1K Citations
Ryuichi Morishita is an academic researcher from Osaka University. The author has contributed to research in topics: Hepatocyte growth factor & Medicine. The author has an hindex of 86, co-authored 676 publications. Previous affiliations of Ryuichi Morishita include Brigham and Women's Hospital & Stanford University.
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Papers
Therapeutic potential of decoy oligonucleotides strategy in cardiovascular diseases
TL;DR: Transfer of the double-stranded ODN corresponding to the cis-sequence will result in attenuation of the authentic cis–trans interaction, leading to removal of trans-factors from the endogenous cis-elements with subsequent modulation of gene expression.
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Therapeutic Effects of Systemic Administration of the Novel RANKL-Modified Peptide, MHP1, for Ischemic Stroke in Mice
Munehisa Shimamura,Hironori Nakagami,Hideo Shimizu,Kouji Wakayama,Tomohiro Kawano,Yuka Ikeda,Hiroki Hayashi,Shota Yoshida,Hideki Mochizuki,Ryuichi Morishita +9 more
TL;DR: The single and successive continuous administration of MHP1 starting from 4 or 6 hours after cerebral ischemia successfully reduced infarct volume and prevented the exacerbation of neurological deficits with reduced activation of microglia/macrophages and inflammatory cytokines.
Contribution of the activation of the ras oncogene to the evolution of aldosterone- and renin-secreting tumors.
Jitsuo Higaki,Akihiro Miya,Tetsuro Miki,Ryuichi Morishita,Hiroshi Mikami,Shin-ichiro Takai,Toshio Ogihara +6 more
TL;DR: The results indicate that point-mutational activation of ras oncogenes does not contribute, at least in this series, towards the evolution of aldosterone-producing adenomas and the reninoma.
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Future Directions of Therapeutic Vaccines for Chronic Diseases.
TL;DR: An original B-cell vaccine to induce antibody production and used carrier proteins, which include exogenous T-cell epitopes through the major histocompatibility complex are introduced and the therapeutic potential for cardiovascular diseases is described.
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Upregulated expression of a subset of genes in APP;ob/ob mice: Evidence of an interaction between diabetes-linked obesity and Alzheimer's disease.
Mitsuru Shinohara,Masataka Kikuchi,Miyuki Onishi-Takeya,Yoshitaka Tashiro,Kaoru Suzuki,Yasuhiro Noda,Shuko Takeda,Masahiro Mukouzono,Seiichi Nagano,Akio Fukumori,Ryuichi Morishita,Akihiro Nakaya,Naoyuki Sato +12 more
- 02 Mar 2021
TL;DR: Data suggest that upregulation of genes uniquely associated with APP;ob/ob mice is an evidence of the interaction between obesity/diabetes and AD.
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