Ryszard Korona
Jagiellonian University
48 Papers
224 Citations
Ryszard Korona is an academic researcher from Jagiellonian University. The author has contributed to research in topics: Gene & Epistasis. The author has an hindex of 22, co-authored 46 publications. Previous affiliations of Ryszard Korona include Michigan State University & University of Massachusetts Amherst.
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Papers
Rapid multiple-level coevolution in experimental populations of yeast killer and nonkiller strains.
Magdalena D. Pieczynska,Magdalena D. Pieczynska,Magdalena D. Pieczynska,Dominika Wloch-Salamon,Ryszard Korona,J. Arjan G. M. de Visser +5 more
TL;DR: The results show that the yeast killer system shows a remarkable potential for rapid multiple‐level coevolution, and it is demonstrated that changes observed in both host and virus were beneficial only when combined, suggesting that they involved reciprocal changes.
An Overexpression Experiment Does Not Support the Hypothesis that Avoidance of Toxicity Determines the Rate of Protein Evolution.
TL;DR: The misfolding avoidance hypothesis postulates that sequence mutations render proteins cytotoxic and therefore the higher the gene expression, the stronger the operation of selection against substitutions, which translates into prediction that relative toxicity of extant proteins is higher for those evolving faster.
Direct Estimate of the Mutation Rate and the Distribution of Fitness Effects in the Yeast Saccharomyces cerevisiae
TL;DR: Estimates of the rate and frequency distribution of deleterious effects were obtained for the first time by direct scoring and characterization of individual mutations by applying tetrad analysis to a large number of yeast clones.
Phage-mediated selection and the evolution and maintenance of restriction-modification.
Ryszard Korona,Bruce R. Levin +1 more
TL;DR: The results of this study are interpreted as support for the hypothesis that the latter, colonization selection, may play an important role in the evolution and maintenance of restriction‐modification.
Low Frequency of Mutations with Strongly Deleterious but Nonlethal Fitness Effects
Angelina Fudala,Ryszard Korona +1 more
TL;DR: The generic paucity of strong effects and abundance of small ones relates to the feasibility of analyses of quantitative traits and epidemiological surveys, irrespective of the particular element of metabolism under study.