Ryo Muranushi
Gunma University
42 Papers
41 Citations
Ryo Muranushi is an academic researcher from Gunma University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 6, co-authored 28 publications.
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Papers
Nintedanib inhibits intrahepatic cholangiocarcinoma aggressiveness via suppression of cytokines extracted from activated cancer-associated fibroblasts
Takahiro Yamanaka,Norifumi Harimoto,Takehiko Yokobori,Ryo Muranushi,Kouki Hoshino,Kei Hagiwara,Dolgormaa Gantumur,Tadashi Handa,Norihiro Ishii,Mariko Tsukagoshi,Takamichi Igarashi,Hiroshi Tanaka,Akira Watanabe,Norio Kubo,Kenichiro Araki,Ken Shirabe +15 more
TL;DR: The findings suggest that therapeutic strategies combining conventional cytotoxic agents with nintedanib targeting CAFs are promising for overcoming refractory ICC with activated CAFs.
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Impact of preoperative nutritional support and rehabilitation therapy in patients undergoing pancreaticoduodenectomy
Mariko Tsukagoshi,Norifumi Harimoto,Kenichiro Araki,Norio Kubo,Akira Watanabe,Takamichi Igarashi,Norihiro Ishii,Takahiro Yamanaka,Kei Hagiwara,Kouki Hoshino,Ryo Muranushi,Toshiki Yajima,Naoki Wada,Ken Shirabe +13 more
TL;DR: In this paper, the impact of preoperative nutritional support and rehabilitation on patients undergoing pancreaticoduodenectomy was investigated, and the authors found that the lack of pre-operative nutrition and prehabilitation was an independent risk factor for postoperative pancreatic fistula.
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Prognostic significance of neutrophil-lymphocyte ratio in resectable pancreatic neuroendocrine tumors with special reference to tumor-associated macrophages.
Norifumi Harimoto,Kouki Hoshino,Ryo Muranushi,Kei Hagiwara,Takahiro Yamanaka,Norihiro Ishii,Mariko Tsukagoshi,Takamichi Igarashi,Hiroshi Tanaka,Akira Watanabe,Norio Kubo,Kenichirou Araki,Yasuo Hosouchi,Hideki Suzuki,Kazuhisa Arakawa,Keitarou Hirai,Takaharu Fukazawa,Hayato Ikota,Ken Shirabe +18 more
TL;DR: NLR is a promising predictor of recurrence after pancreatectomy that needs to be further investigated and that accumulation of TAMs in the tumor could be one of the causes of NLR elevation.
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Conophylline inhibits hepatocellular carcinoma by inhibiting activated cancer-associated fibroblasts through suppression of G Protein-Coupled Receptor 68
Takahiro Yamanaka,Norifumi Harimoto,Takehiko Yokobori,Ryo Muranushi,Kouki Hoshino,Kei Hagiwara,Dolgormaa Gantumur,Tadashi Handa,Norihiro Ishii,Mariko Tsukagoshi,Takamichi Igarashi,Akira Watanabe,Norio Kubo,Kenichiro Araki,Kazuo Umezawa,Ken Shirabe +15 more
TL;DR: Conophylline (CnP), a vinca alkaloid obtained from Ervatamia microphylla leaves, has been reported to suppress activation of hepatic stellate cells and liver fibrosis in rats.
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High Co-expression of Large Tenascin C Splice Variants in Stromal Tissue and Annexin A2 in Cancer Cell Membranes is Associated with Poor Prognosis in Pancreatic Cancer.
Kei Hagiwara,Norifumi Harimoto,Takehiko Yokobori,Ryo Muranushi,Kouki Hoshino,Dorgormaa Gantumur,Takahiro Yamanaka,Norihiro Ishii,Mariko Tsukagoshi,Takamichi Igarashi,Hiroshi Tanaka,Akira Watanabe,Norio Kubo,Kenichiro Araki,Yasuo Hosouchi,Ken Shirabe +15 more
TL;DR: The data suggest that co-expression of stromal TNC-L and membranous ANXA2 is a poor prognostic marker compared with detection of T NC-L or ANxA2 alone for pancreatic cancer patients, and targeting of crosstalk between stromAL TNC and cancer cell ANXa2 could be a promising therapeutic strategy to overcome refractory pancreaticcancer.
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