Ryan R. Cheng
Rice University
40 Papers
104 Citations
Ryan R. Cheng is an academic researcher from Rice University. The author has contributed to research in topics: Chromatin & Genome. The author has an hindex of 19, co-authored 38 publications. Previous affiliations of Ryan R. Cheng include University of California, Santa Barbara & University of Texas at Austin.
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Papers
The Energetics and Physiological Impact of Cohesin Extrusion
Laura Vian,Aleksandra Pekowska,Suhas S.P. Rao,Suhas S.P. Rao,Kyong-Rim Kieffer-Kwon,Seolkyoung Jung,Laura Baranello,Su-Chen Huang,Laila El Khattabi,Marei Dose,Nathanael Pruett,Adrian L. Sanborn,Adrian L. Sanborn,Andres Canela,Yaakov Maman,Anna Oksanen,Wolfgang Resch,Xingwang Li,Byoungkoo Lee,Alexander L. Kovalchuk,Zhonghui Tang,Steevenson Nelson,Michele Di Pierro,Ryan R. Cheng,Ido Machol,Brian Glenn St Hilaire,Neva C. Durand,Muhammad S. Shamim,Elena Stamenova,José N. Onuchic,Yijun Ruan,André Nussenzweig,David Levens,Erez Lieberman Aiden,Erez Lieberman Aiden,Erez Lieberman Aiden,Rafael Casellas +36 more
TL;DR: It is proposed that higher organisms have coopted cohesin extrusion to enhance transcription and recombination, with implications for tumor development.
563
Quantifying internal friction in unfolded and intrinsically disordered proteins with single-molecule spectroscopy.
Andrea Soranno,Brigitte Buchli,Daniel Nettels,Ryan R. Cheng,Sonja Müller-Späth,Shawn H. Pfeil,Armin Hoffmann,Everett A. Lipman,Dmitrii E. Makarov,Benjamin Schuler +9 more
TL;DR: The combination of single-molecule Förster resonance energy transfer, nanosecond fluorescence correlation spectroscopy, and microfluidic mixing is used to determine the reconfiguration times of unfolded proteins and investigate the mechanisms of internal friction contributing to their dynamics.
345
De novo prediction of human chromosome structures: Epigenetic marking patterns encode genome architecture.
Michele Di Pierro,Ryan R. Cheng,Erez Lieberman Aiden,Erez Lieberman Aiden,Peter G. Wolynes,José N. Onuchic +5 more
TL;DR: It is demonstrated that it is possible to predict how a genome will fold based on the epigenetic marks that decorate chromatin, and that de novo structure prediction for whole genomes may be increasingly possible.
242
De Novo Prediction of Human Chromosome Structures: Epigenetic Marking Patterns Encode Genome Architecture
TL;DR: It is shown that this chromatin architecture can be predicted de novo using epigenetic data derived from ChIP-Seq, and strongly suggest that epigenetic marking patterns encode sufficient information to determine the global architecture of chromosomes and that de noovo structure prediction for whole genomes may be increasingly possible.
134
Aggregation Effects on the Emission Spectra and Dynamics of Model Oligomers of MEH-PPV
Gizelle A. Sherwood,Ryan R. Cheng,Timothy M. Smith,James H. Werner,Andrew P. Shreve,Linda A. Peteanu,Jurjen Wildeman +6 more
TL;DR: In this paper, the effects of aggregation formation on photophysical properties of oligomers of MEH-PPV were studied in bulk solution to better understand the effect of aggregation on the emission properties of the polymer.
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