Ryan Hausler
University of Pennsylvania
29 Papers
26 Citations
Ryan Hausler is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 3, co-authored 10 publications. Previous affiliations of Ryan Hausler include United States Department of Veterans Affairs & University of Pittsburgh.
Chat about Author
Papers
Association of Inherited Mutations in DNA Repair Genes with Localized Prostate Cancer.
Daniel J. Lee,Ryan Hausler,Anh N Le,Gregory Kelly,Jacquelyn Powers,James Ding,Emily Feld,Heena Desai,Casey Morrison,Abigail Doucette,Peter Gabriel,Renae Judy,JoEllen Weaver,Rachel L. Kember,Scott M. Damrauer,Scott M. Damrauer,Daniel J. Rader,Susan M. Domchek,Vivek Narayan,Lauren E. Schwartz,Kara N. Maxwell +20 more
TL;DR: In this article, a cross-sectional study of 2391 localized prostate cancer patients and 3,273 cancer-free males was carried out to determine DNA repair genes associated with localized Prostate Cancer (PrCa) in a diverse academic biobank and to determine genetic testing burden.
23
Inherited TP53 Variants and Risk of Prostate Cancer
Kara N. Maxwell,Kara N. Maxwell,Heather H. Cheng,Heather H. Cheng,Jacquelyn Powers,Roman Gulati,Elisa Ledet,Casey Morrison,Anh D. Le,Ryan Hausler,Ryan Hausler,Jill E. Stopfer,Sophie Hyman,Wendy Kohlmann,Anne Naumer,Jennie Vagher,Samantha Greenberg,Lorraine V. Naylor,Mercy Y. Laurino,Eric Q. Konnick,Brian H. Shirts,Saud H. AlDubayan,Saud H. AlDubayan,Eliezer M. Van Allen,Eliezer M. Van Allen,Bastien Nguyen,Joseph Vijai,Wassim Abida,Maria I. Carlo,Marianne E Dubard-Gault,Marianne E Dubard-Gault,Daniel J. Lee,Daniel J. Lee,Luke Maese,Luke Maese,Diana Mandelker,Bruce Montgomery,Bruce Montgomery,Michael J. Morris,Piper Nicolosi,Robert L. Nussbaum,Lauren E. Schwartz,Zsofia K. Stadler,Judy Garber,Kenneth Offit,Joshua D. Schiffman,Joshua D. Schiffman,Peter S. Nelson,Peter S. Nelson,Oliver Sartor,Michael Walsh,Colin C. Pritchard +51 more
TL;DR: In this paper, a multi-institutional retrospective study characterizes prostate cancer incidence in a cohort of Li-Fraumeni syndrome (LFS) males and gTP53 prevalence in a prostate cancer cohort.
20
Postvaccination graft dysfunction/aplastic anemia relapse with massive clonal expansion of autologous CD8+ lymphocytes.
Caitlin Ritz,Caitlin Ritz,Wenzhao Meng,Natasha Stanley,Natasha Stanley,Miren L. Baroja,Chong Xu,Patrick Yan,Alexander C. Huang,Alexander C. Huang,Ryan Hausler,Peter Nicholas,Jian-Meng Fan,David B. Lieberman,Beatriz M. Carreno,Beatriz M. Carreno,Eline T. Luning Prak,Timothy S. Olson,Daria V. Babushok,Daria V. Babushok +19 more
TL;DR: Acquired aplastic anemia is a T-cell–mediated autoimmune bone marrow aplasia, without a known etiologic trigger, that can occur following vaccination and accompany graft dysfunction or aplastics anemia relapse.
20
Upper Gastrointestinal Cancer Risk and Surveillance Outcomes in Li-Fraumeni Syndrome.
Bryson W. Katona,Jacquelyn Powers,Danielle McKenna,Jessica M. Long,Anh N Le,Ryan Hausler,Kristin Zelley,Sarah Jennings,Susan M. Domchek,Katherine L. Nathanson,Suzanne P. MacFarland,Kara N. Maxwell +11 more
TL;DR: UGI cancer is observed in Li-Fraumeni syndrome and upper endoscopy should be part of a comprehensive LFS surveillance program.
14
DataRemix: a universal data transformation for optimal inference from gene expression datasets
TL;DR: This work describes a generalization of SVD-based reconstruction for which the common techniques of whitening, rank-k approximation, and removing the top k principle components are special cases and demonstrates that the simple three-parameter transformation, DataRemix, can be tuned to reweight the contribution of hidden factors and reveal otherwise hidden biological signals.
5