Ryan E. Longman
National Institutes of Health
13 Papers
524 Citations
Ryan E. Longman is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Arthritis & Genetic linkage. The author has an hindex of 8, co-authored 10 publications.
Chat about Author
Papers
A genome scan localizes five non-MHC loci controlling collagen-induced arthritis in rats.
Elaine F. Remmers,Ryan E. Longman,Ying Du,Ann M. O’Hare,Grant W. Cannon,Marie M. Griffiths,Ronald L. Wilder +6 more
TL;DR: Characterization of the genes underlying these QTLs will facilitate the identification of key biochemical pathways regulating experimental autoimmune arthritis in rats and may provide insights into RA and other human autoimmune diseases.
218
•Journal Article
Localization of Quantitative Trait Loci Regulating Adjuvant-Induced Arthritis in Rats: Evidence for Genetic Factors Common to Multiple Autoimmune Diseases
Yutaka Kawahito,Grant W. Cannon,Pércio S. Gulko,Elaine F. Remmers,Ryan E. Longman,Van Reese,Jianping Wang,Marie M. Griffiths,Ronald L. Wilder +8 more
TL;DR: Rat models appear to provide a powerful complementary approach to identify and characterize candidate genes that may contribute to autoimmune diseases in several species, and an analysis of conserved synteny among rats, mice, and humans suggested that Aia2 and Aia3/Cia3, like Aia1/CIA1, contain candidate genes for several autoimmune/inflammatory diseases in mice and humans.
117
Identification of a new non-major histocompatibility complex genetic locus on chromosome 2 that controls disease severity in collagen-induced arthritis in rats
Pércio S. Gulko,Yutaka Kawahito,Elaine F. Remmers,Van Reese,Jianping Wang,Svetlana Dracheva,Lynn Ge,Ryan E. Longman,Jennifer S. Shepard,Grant W. Cannon,Allen D. Sawitzke,Ronald L. Wilder,Marie M. Griffiths +12 more
TL;DR: This rat model should facilitate positional cloning and functional characterization of regulatory genes that may play a role in several forms of autoimmune disease, including rheumatoid arthritis.
79
Identification of a new quantitative trait locus on chromosome 7 controlling disease severity of collagen-induced arthritis in rats.
Svetlana Dracheva,Elaine F. Remmers,Pércio S. Gulko,Yutaka Kawahito,Ryan E. Longman,Van Reese,Grant W. Cannon,Marie M. Griffiths,Ronald L. Wilder +8 more
TL;DR: A new non-MHC quantitative trait locus, Cia8, is described on rat Chromosome (Chr) 7 that controls collagen-induced arthritis severity in F2 progeny of DA and F344 inbred rats, and an updated localization of Cia4 on the same chromosome is presented.
35
Localization in rats of genetic loci regulating susceptibility to experimental erosive arthritis and related autoimmune diseases
Ronald L. Wilder,Marie M. Griffiths,Elaine F. Remmers,Grant W. Cannon,Rachel R. Caspi,Yutaka Kawahito,Pércio S. Gulko,Ryan E. Longman,Svetlana Dracheva,Y Du,Shu Hui Sun,Jianping Wang,Jennifer S. Shepard,Bina Joe,Lynn Ge,Stephen Chen,Lisa Chang,Jean H. Hoffman,Phyllis B. Silver,Van Reese +19 more
- 01 May 1999
29