Ryan A. Harris
Prevention Institute
11 Papers
26 Citations
Ryan A. Harris is an academic researcher from Prevention Institute. The author has contributed to research in topics: Exercise intolerance & Aerobic exercise. The author has an hindex of 4, co-authored 11 publications.
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Papers
VO2max as an exercise tolerance endpoint in people with cystic fibrosis: Lessons from a lumacaftor/ivacaftor trial.
John W Wilson,John W Wilson,X You,Matt J. Ellis,Don S. Urquhart,Lokesh Jha,Margaret E. Duncan,S. Tian,Ryan A. Harris,Tom Kotsimbos,Dominic Keating +10 more
TL;DR: In this article, the authors conducted a multisite Phase 4 trial comparing the impact of lumacaftor/ivacaftors on exercise tolerance with that of placebo in participants ≥ 12 years of age with CF homozygous for F508del-CFTR.
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Angiotensin II receptor blocker attenuates stress pressor response in young adult African Americans.
Jin Hee Jeong,Coral Hanevold,Ryan A. Harris,Gaston Kapuku,Jennifer S. Pollock,David M. Pollock,Gregory A. Harshfield +6 more
TL;DR: The hypothesis that activation of RAS is a potential contributing factor for altered CV responses to stress, and suppression of angiotensin II (Ang II) activity will improve hemodynamic responses to a prolonged mental stressor in healthy young AAs is tested.
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Obesity and the Bidirectional Risk of Cancer and Cardiovascular Diseases in African Americans: Disparity vs. Ancestry.
Avirup Guha,Avirup Guha,Xiaoling Wang,Ryan A. Harris,Anna-Gay Nelson,David W. Stepp,Zachary Klaassen,Priyanka Raval,Jorge E. Cortes,Steven S. Coughlin,Vladimir Y. Bogdanov,Justin Xavier Moore,Nihar R. Desai,D. Douglas Miller,Xin Yun Lu,Ha Won Kim,Neal L. Weintraub +16 more
TL;DR: In this article, the authors present the evidence regarding obesity-related disparities in the bidirectional risk of CVD and cancer and also discuss the potential association of gene polymorphisms in AAs with emphasis on ACKR1.
Sildenafil improves exercise capacity in patients with cystic fibrosis: a proof-of-concept clinical trial:
Paula Rodriguez-Miguelez,Haruki Ishii,Nichole Seigler,Reva Crandall,Jeffrey Thomas,Caralee Forseen,Kathleen T. McKie,Ryan A. Harris +7 more
TL;DR: This proof-of-concept clinical trial demonstrates that sildenafil treatment can improve exercise capacity in patients with CF and that pulmonary function may play an important role in the effectiveness of treatment.
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Oxygen transport and utilisation during exercise in cystic fibrosis: contributors to exercise intolerance
TL;DR: This review highlights the central and peripheral mechanisms that alter oxygen transport and utilisation and thereby contribute to exercise limitation in people with cystic fibrosis, considering also viable therapeutic targets for intervention.
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