Ryan A. Bronson
Broad Institute
6 Papers
4 Citations
Ryan A. Bronson is an academic researcher from Broad Institute. The author has contributed to research in topics: Biology & Microbiome. The author has an hindex of 1, co-authored 2 publications.
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Papers
Longitudinal multi-omics analyses link gut microbiome dysbiosis with recurrent urinary tract infections in women
Colin J. Worby,Henry L. Schreiber,Timothy J. Straub,Lucas R. van Dijk,Ryan A. Bronson,Benjamin S Olson,Jerome S. Pinkner,C. Obernuefemann,Vanessa L. Muñoz,Alexandra E. Paharik,Philippe Azimzadeh,Bruce J. Walker,Christopher A. Desjardins,Wen-Chi Chou,Karla Bergeron,Sinéad B. Chapman,Aleksandra Klim,Abigail L. Manson,Thomas J. Hannan,Thomas M. Hooton,Andrew L. Kau,H. Henry Lai,Karen W. Dodson,Scott J. Hultgren,Ashlee M. Earl +24 more
TL;DR: In this paper , the role of the microbiota in recurrent urinary tract infections (rUTIs) remains unclear, and the authors conducted a year-long study of women with and without a history of rUTI, from whom they collected urine, blood and monthly faecal samples for metagenomic and transcriptomic interrogation.
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Global phylogenomic analyses of Mycobacterium abscessus provide context for non cystic fibrosis infections and the evolution of antibiotic resistance.
Ryan A. Bronson,Chhavi Gupta,Abigail L. Manson,Jan A. Nguyen,Asli Bahadirli-Talbott,Nicole Parrish,Ashlee M. Earl,Keira A. Cohen +7 more
TL;DR: In this paper, the authors construct a global dataset of 1,279 MAB whole genomes from CF or non-CF patients and utilize whole genome analysis to assess relatedness, phylogeography, and drug resistance evolution.
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Gut microbiome perturbation, antibiotic resistance, and Escherichia coli strain dynamics associated with international travel: a metagenomic analysis
Colin J. Worby,Sushmita Sridhar,Sarah E Turbett,Margaret V Becker,Lucyna Kogut,Vanessa Sanchez,Ryan A. Bronson,Elizabeth Oliver,Allison Taylor Walker,Maroya Spalding Walters,Paul Kelly,Daniel T Leung,M. Knouse,Stefan H F Hagmann,Jason B Harris,Edward T. Ryan,Ashlee M. Earl,Regina C. LaRocque +17 more
TL;DR: A perturbation of the gut microbiota is observed, characterised by a significant depletion of microbial diversity and enrichment of the Enterobacteriaceae family, which highlights a scale of E coli and antimicrobial-resistant organism acquisition by US travellers not apparent from previous culture-based studies.
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Gut-bladder axis syndrome associated with recurrent UTIs in humans
Colin J. Worby,Henry L. Schreiber,Henry L. Schreiber,Timothy J. Straub,Lucas R. van Dijk,Lucas R. van Dijk,Ryan A. Bronson,Benjamin Olson,Jerome S. Pinkner,Chloe L. P. Obernuefemann,Vanessa L. Muñoz,Alexandra E. Paharik,Bruce J. Walker,Christopher A. Desjardins,Wen-Chi Chou,Karla Bergeron,Sinéad B. Chapman,Aleksandra Klim,Abigail L. Manson,Thomas J. Hannan,Thomas M. Hooton,Andrew L. Kau,H. Henry Lai,Karen W. Dodson,Scott J. Hultgren,Ashlee M. Earl +25 more
TL;DR: In this paper, a year-long study of women with and without history of rUTIs, from whom they collected urine, blood and monthly fecal samples for multi-omic interrogation.
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Distinct Escherichia coli transcriptional profiles in the guts of recurrent UTI sufferers revealed by pan-genome hybrid selection
Mark G. Young,Timothy J. Straub,Colin J. Worby,Hayden C. Metsky,Andreas Gnirke,Ryan A. Bronson,Lucas R. van Dijk,Christopher A. Desjardins,Christian Matranga,James Qu,Karen W. Dodson,Henry L. Schreiber,Abigail L. Manson,Scott J. Hultgren,Ashlee M. Earl +14 more
TL;DR: E. coli PanSelect is a novel method to enrich and study low-abundance E. coli in human gut microbiomes. It holds promise for investigations of native in vivo biology and differential gene expression in diverse E. coli populations.
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