Ruud M. Ramakers
Utrecht University
31 Papers
123 Citations
Ruud M. Ramakers is an academic researcher from Utrecht University. The author has contributed to research in topics: Imaging phantom & Iterative reconstruction. The author has an hindex of 11, co-authored 24 publications. Previous affiliations of Ruud M. Ramakers include Delft University of Technology & University Medical Center Utrecht.
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Papers
VECTor: A Preclinical Imaging System for Simultaneous Submillimeter SPECT and PET
Marlies C Goorden,Frans van der Have,R. Kreuger,Ruud M. Ramakers,Brendan Vastenhouw,J. Peter H. Burbach,Jan Booij,Carla F. M. Molthoff,Freek J. Beekman +8 more
TL;DR: A Versatile Emission Computed Tomography system (VECTor) for radionuclides that enables simultaneous submillimeter imaging of single-photon and positron-emitting radiolabeled molecules and pave the way for new perspectives in imaging the biologic systems of rodents.
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Ultra-High-Sensitivity Submillimeter Mouse SPECT
Oleksandra Ivashchenko,Oleksandra Ivashchenko,Frans van der Have,Marlies C Goorden,Ruud M. Ramakers,Freek J. Beekman +5 more
TL;DR: A dedicated ultra-high-sensitivity pinhole SPECT that increases the range of mouse SPECT applications by enabling in vivo imaging with less than a megabecquerel of tracer activity or down to 1-s frame dynamics.
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Fast Spiral SPECT with Stationary γ-Cameras and Focusing Pinholes
Pieter Vaissier,Marlies C Goorden,Brendan Vastenhouw,Frans van der Have,Ruud M. Ramakers,Freek J. Beekman +5 more
TL;DR: In this paper, the authors developed and tested spiral trajectories (STs) of the animal bed requiring fewer steps to improve temporal resolution and reduce image reconstruction time for such scans.
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3-D Rat Brain Phantom for High-Resolution Molecular Imaging
Freek J. Beekman,Brendan Vastenhouw,G. van der Wilt,Marcia Vervloet,R. Visscher,Jan Booij,M.A.F.M. Gerrits,Changguo Ji,Ruud M. Ramakers,F. van der Have +9 more
- 06 Oct 2009
TL;DR: A newly developed brain phantom will enable the optimization of high-resolution imaging for recovery of complex shaped molecular distributions, and is presented to represent, e.g., cerebral blood flow, glucose metabolism, or neuroreceptor binding in small regions of the rat brain.
High-resolution clustered pinhole 131Iodine SPECT imaging in mice
Frans van der Have,Frans van der Have,Oleksandra Ivashchenko,Oleksandra Ivashchenko,Marlies C Goorden,Ruud M. Ramakers,Ruud M. Ramakers,Freek J. Beekman,Freek J. Beekman +8 more
TL;DR: High-resolution quantitative and fast dynamic (131)I SPECT in mice is possible by means of a high-energy collimator and optimized system modeling, which enables analysis of ( 131)I uptake even within small organs in mice, which can be highly valuable for development and optimization of targeted cancer therapies.
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