Ruth P. Cusack
McMaster University
32 Papers
20 Citations
Ruth P. Cusack is an academic researcher from McMaster University. The author has contributed to research in topics: Asthma & Medicine. The author has an hindex of 3, co-authored 15 publications. Previous affiliations of Ruth P. Cusack include St. Joseph's Healthcare Hamilton.
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Papers
Under- and over-diagnosis of COPD: a global perspective
TL;DR: There is large variation in the prevalence of COPD, with 10–95% under-diagnosis and 5–60% over- Diagnosis due to differences in the definition of diagnosis used, and the unavailability of spirometry in rural areas of low- and middle-income countries where the prevalenceof COPD is likely to be high.
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The Role of Airway Epithelial Cell Alarmins in Asthma
TL;DR: With genome-wide association studies demonstrating associations between single-nucleotide polymorphisms of the TSLP and IL-33 gene and risk of asthma, it will be important to understand which subsets of asthma patients will benefit most from anti-alarmin therapy.
The Genetic Factors of the Airway Epithelium Associated with the Pathology of Asthma
TL;DR: A review of the genetics of asthma in relation to risk, response to common treatments, and gene-environmental interactions can be found in this article , where the complexity in the etiology of asthma also results from interactions between environmental and genetic factors.
Regulation of Eosinophilia in Asthma-New Therapeutic Approaches for Asthma Treatment.
TL;DR: In this paper, the IL-5 pathway has been shown to support eosinophilia and is responsible for terminal differentiation of human eOSinophils, regulating eosINophil proliferation, differentiation, maturation, migration, and prevention of cellular apoptosis.
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