Ruijie Chen
Wenzhou Medical College
60 Papers
14 Citations
Ruijie Chen is an academic researcher from Wenzhou Medical College. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 11, co-authored 40 publications.
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Papers
Therapeutic options and drug delivery strategies for the prevention of intrauterine adhesions
TL;DR: The traditional intervention methods for the prevention of IUAs, as well as novel therapeutics and delivery strategies that will most likely change the treatment paradigms for better clinical outcomes are discussed.
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Biomaterial-engineered intra-articular drug delivery systems for osteoarthritis therapy.
TL;DR: It is urgent to establish a suitable and efficient drug delivery system for OA therapy, and attention is paid to various types of drug delivery systems and potential therapeutic drugs that may escalate OA treatments.
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Ambidextrous Approach To Disrupt Redox Balance in Tumor Cells with Increased ROS Production and Decreased GSH Synthesis for Cancer Therapy
Longfa Kou,Longfa Kou,Rui Sun,Shuyi Xiao,Ya-Wen Zheng,Zhiwei Chen,Aimin Cai,Hailun Zheng,Qing Yao,Vadivel Ganapathy,Ruijie Chen +10 more
TL;DR: Treatment of tumor cells with SASP/ZnO NPs in vitro and in vivo resulted in a synergistic disruptive effect on redox balance in tumor cells and induced cell death and decreased tumor growth.
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Intra-articular drug delivery systems for osteoarthritis therapy: shifting from sustained release to enhancing penetration into cartilage
TL;DR: The development of sustained-release drug delivery systems (DDSs) for OA may be an attractive strategy to prevent rapid drug clearance and improve the half-life of a drug at the joint cavity to promote the development of effective OA drugs in the future.
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Opsonized nanoparticles target and regulate macrophage polarization for osteoarthritis therapy: A trapping strategy.
Longfa Kou,Huirong Huang,Ying Zhong Tang,Meng Sun,Yingtao Li,Jianing Wu,Shimin Zheng,Xin Zhao,Daosen Chen,Zucheng Luo,Xiaolei Zhang,Qing Yao,Ruijie Chen +12 more
TL;DR: In this paper , a novel opsonization trapping strategy for osteoarthritis drug delivery and treatment is proposed, which transforms a normal nanoparticle into an opsonized attractant to target and regulate macrophage polarization.
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