Ruifeng Li
Peking University
12 Papers
11 Citations
Ruifeng Li is an academic researcher from Peking University. The author has contributed to research in topics: Chromatin & Genome. The author has an hindex of 7, co-authored 9 publications.
Chat about Author
Papers
Nuclear actin regulates inducible transcription by enhancing RNA polymerase II clustering
Mian Wei,Xiaoying Fan,Miao Ding,Ruifeng Li,Shipeng Shao,Yingping Hou,Shaoshuai Meng,Fuchou Tang,Cheng Li,Yujie Sun +9 more
TL;DR: This work unveils that nuclear actin promotes the formation of transcription factory on inducible genes, acting as a general mechanism underlying the rapid response to environmental cues.
110
Nuclear peripheral chromatin-lamin B1 interaction is required for global integrity of chromatin architecture and dynamics in human cells.
Lei Chang,Mengfan Li,Shipeng Shao,Chen Li,Shanshan Ai,Boxin Xue,Yingping Hou,Yiwen Zhang,Ruifeng Li,Xiaoying Fan,Aibin He,Cheng Li,Yujie Sun +12 more
TL;DR: It is proved that depletion of lamin B1 leads to increased chromatin dynamics, owing to chromatin decompaction and redistribution toward nucleoplasm, and the inter-chromosomal as well as inter-compartment interactions are increased, but the structure of topologically associating domains (TADs) is not affected.
STAT3 regulates CD8+ T cell differentiation and functions in cancer and acute infection.
Qinli Sun,Xiaohong Zhao,Ruifeng Li,Dingfeng Liu,Birui Pan,Bowen Xie,Xinxin Chi,Dong Li Cai,Peng Wei,Wei Xu,Kun Wei,Zixuan Zhao,Yujie Fu,Ling Ni,Chen Dong +14 more
TL;DR: The role of STAT3 signaling in the development and function of terminally differentiated effector CD8+ T cells in acute infection was investigated in this paper , where it was found that STAT3 transcriptionally promotes the expression of effector function-related genes, while it suppresses those expressed by the progenitor Tex subset.
50
The exon junction complex regulates the splicing of cell polarity gene DLG1 to control Wingless signaling in development
TL;DR: Genetic and biochemical experiments demonstrate that Dlg1 protein acts independently from its role in cell polarity to protect Dsh protein from lysosomal degradation, and reveal a conserved regulatory mechanism of Wg/Wnt signaling by DlG and EJC.
In vivo G-CSF treatment activates the GR-SOCS1 axis to suppress IFN-γ secretion by natural killer cells.
Xiang-Yu Zhao,Ting Peng,Xun-Hong Cao,Yingping Hou,Ruifeng Li,Ting-Ting Han,Zeying Fan,Ming Zhao,Ying-Tang Chang,Hebin Chen,Cheng Li,Xiaojun Huang +11 more
TL;DR: In this paper , the authors identify a pathway that is activated in response to Granulocyte Colony Stimulating Factor (G-CSF) treatment, which suppresses IFN-γ secretion in NK cells.
10