Osteoarthritis is the most common form of arthritis and is a substantial burden for patients with the disease. Currently, there is no cure for osteoarthritis, but many emerging therapies have been developed to aid in the mitigation of disease progression. When osteoarthritis reaches the end-stage of disease many patients undergo total joint arthroplasty to improve quality of life, yet some experience persistent pain and mobility limitations for extended periods following surgery. This review highlights recent therapeutic advancements in osteoarthritis treatment consisting of pharmacologics, nutraceuticals, biologics, and exercise while emphasizing the current state of post-arthroplasty rehabilitation.

/pdf/osteoarthritis-progression-mitigation-and-rehabilitation-135bt0aqks.pdf

Osteoarthritis Progression: Mitigation and Rehabilitation Strategies

.Osteoarthritis (OA) is a prevalent chronic joint condition resulting in pain, stiffness, and reduced joint function. Kinesio taping (KT) has emerged as an adjunct treatment for OA. Objective: To examine the role of KT as an adjunctive intervention in the physiotherapy management of knee OA. Methods: A quasi-experimental investigation was conducted at Bethania Hospital, Pakistan, comparing the effectiveness of standard physiotherapy alone (Group 1) and standard physiotherapy plus KT (Group 2) in patients with knee OA grade I and II. By convenience sampling selected 50 participants aged above 40 with knee OA. Both groups received standard physiotherapy treatments, and KT was applied to Group 2 using a specific technique. Outcome measures included pain reduction Visual Analogue Scale (VAS), functional improvement using Western Ontario and McMaster Index (WOMAC), and presence of swelling and tenderness. Results: Demographic findings showed left-sided predominance of knee involvement, higher female prevalence, and a common age group of 40-45 years. Both groups demonstrated improvement in pain and functional outcomes post-intervention. The experimental group (Group 2) exhibited significantly lower WOMAC scores (p <.001) and VAS pain scores (p=.011) compared to the control group indicating superior improvement. The incidence of swelling and tenderness around knee demonstrated no improvement in posttest analysis. Conclusions: Promising results are reported in KT group in management of knee OA in grade I and grade II as compared to only physiotherapy treatment. The study highlights the age specific considerations, tape application method and impact of kinesio tape intervention as an additional option in physiotherapy.  

Exploring the Efficacy of Kinesio Taping as an Adjunct Treatment for Knee Osteoarthritis, Grade 1 & 2: A Quasi-Experimental Study

To investigate whether risk factors related to pain vary at different stages of knee osteoarthritis (OA).

Pain‐Related Risk Factors Among Radiologic Stages of Knee Osteoarthritis: Data From the Osteoarthritis Initiative

Knee osteoarthritis (OA) is a chronic and prevalent musculoskeletal condition that is the underlying cause of disability in most patients worldwide. Even though the pathophysiology of KOA has not yet been fully understood and includes a wide range of risk factors, current therapeutic options are temporarily palliative rather than curative. In recent years, new strategies have focused on the curative agents. As part of this review, we highlight the latest treatment approaches for KOA.

New Horizons in Treatment of Knee Osteoarthritis: A Brief Look-up at Emerging Approaches

Osteoarthritis (OA) is one of the major diseases leading to disability, and inflammation plays an important role in the pathogenesis of OA. However, inflammation of OA is multifactorial, chronic, and in low intensity, which makes drug-based immunotherapy difficult. Here, we have designed a novel method of exercise—static low angle squat (SLAS), which reduces the intra-articular inflammation of OA knee as well as strengthens the vastus medialis of quadriceps. A two-year follow-up trial of current exercise methods demonstrated long-term, significant improvement in pain relief, range of motion, muscle strength, and knee stability.

/pdf/static-low-angle-squatting-reduces-the-intra-articular-4ius994kyp.pdf

Static Low-Angle Squatting Reduces the Intra-Articular Inflammatory Cytokines and Improves the Performance of Patients with Knee Osteoarthritis.

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Static Low-Angle Squatting Reduces the Intra-Articular Inflammatory Cytokines and Improves the Performance of Patients with Knee Osteoarthritis.