Ruhani Singh
University of Western Australia
11 Papers
Ruhani Singh is an academic researcher from University of Western Australia. The author has contributed to research in topics: Chemistry & Targeted drug delivery. The author has an hindex of 5, co-authored 7 publications. Previous affiliations of Ruhani Singh include Commonwealth Scientific and Industrial Research Organisation.
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Papers
Distinction Between Active and Passive Targeting of Nanoparticles Dictate Their Overall Therapeutic Efficacy
Tristan D. Clemons,Ruhani Singh,Ruhani Singh,Anabel Sorolla,Nutan Chaudhari,Alysia Hubbard,K. Swaminatha Iyer +6 more
TL;DR: It is demonstrated that the intracellular destination of nanoparticles beyond its ability to internalize is an important parameter that has to be accounted for in the design of targeted drug delivery systems.
Nanoparticle-Mediated Dual Delivery of an Antioxidant and a Peptide against the L-Type Ca2+ Channel Enables Simultaneous Reduction of Cardiac Ischemia-Reperfusion Injury
Naviin Hardy,Helena M. Viola,Victoria P.A. Johnstone,Tristan D. Clemons,Henrietta Cserne Szappanos,Ruhani Singh,Nicole M. Smith,K. Swaminathan Iyer,Livia C. Hool +8 more
TL;DR: It is demonstrated in isolated rat hearts exposed to ischemia followed by reperfusion, that curcumin and the AID peptide in combination effectively reduce muscle damage, decrease oxidative stress and superoxide production in cardiac myocytes.
Dose‐Dependent Therapeutic Distinction between Active and Passive Targeting Revealed Using Transferrin‐Coated PGMA Nanoparticles
Ruhani Singh,Marck Norret,Michael J. House,Yuriy Galabura,Michael Bradshaw,Diwei Ho,Robert C. Woodward,Timothy G. St. Pierre,Igor Luzinov,Nicole M. Smith,Lee Yong Lim,Killugudi Swaminathan Iyer +11 more
TL;DR: It is demonstrated that dosage is a pivotal parameter that needs to be taken into account in the assessment of nanoparticle mediated targeted drug delivery.
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Biomimetic Metal-Organic Frameworks as Protective Scaffolds for Live-Virus Encapsulation and Vaccine Stabilization.
Ruhani Singh,Jacinta F. White,Malisja de Vries,Gary Beddome,Meiling Dai,Andrew G. D. Bean,Xavier Mulet,D. Layton,Cara M. Doherty +8 more
TL;DR: In this paper , a biomimetic-mineralization of live-viral vaccines using metal-organic frameworks (MOFs) to enhance their storage stability from days to months was reported.
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Functional Reactive Polymer Electrospun Matrix
Vipul Agarwal,Dominic Ho,Diwei Ho,Yuriy Galabura,Faizah Md Yasin,Peijun Gong,Weike Ye,Ruhani Singh,Alaa M. Munshi,Martin Saunders,Robert C. Woodward,Timothy G. St. Pierre,Fiona M. Wood,Mark W. Fear,Dirk Lorenser,David D. Sampson,Bogdan Zdyrko,Igor Luzinov,Nicole M. Smith,K. Swaminathan Iyer +19 more
TL;DR: The utility of electrospun poly(glycidyl methacrylate) films as a highly versatile platform for the development of functional nanostructured materials anchored to a surface is demonstrated and functional nanocomposites can be fabricated using this platform with properties for sensing, fluorescence imaging, and magneto-responsiveness.
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