Rudolf Gmür
University of Zurich
65 Papers
988 Citations
Rudolf Gmür is an academic researcher from University of Zurich. The author has contributed to research in topics: Dental plaque & Biofilm. The author has an hindex of 34, co-authored 65 publications. Previous affiliations of Rudolf Gmür include National Research Council & Academic Center for Dentistry Amsterdam.
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Papers
Oral Biofilm Architecture on Natural Teeth
Vincent Zijnge,M. Barbara M. van Leeuwen,John E. Degener,Frank Abbas,Thomas Thurnheer,Rudolf Gmür,Hermie J. M. Harmsen +6 more
TL;DR: In vivo observations on oral biofilms provide a clear vision on biofilm architecture and the spatial distribution of predominant species and identified for the first time in vivo that Lactobacillus sp.
Multiplex FISH analysis of a six-species bacterial biofilm.
TL;DR: Results show that the simultaneous investigation by FISH of complex biofilms composed of multiple bacterial species with differential Gram-staining properties is possible and holds great promise for the analysis of spatial alterations in biofilm composition in response to environmental challenges.
235
Mass Transport of Macromolecules within an In Vitro Model of Supragingival Plaque
TL;DR: Analysis of diffusion phenomena through the biofilms suggested tortuosity as the most probable explanation for retarded diffusion, as selective attenuated diffusion of fermentable carbohydrates and acids produced within dental plaque is thought to be essential for the development of carious lesions.
Prevalence of Bacteroides forsythus and Bacteroides gingivalis in subgingival plaque of prosthodontically treated patients on short recall.
TL;DR: Overall, B. forsythus was found to colonize lesions earlier, that is at smaller probing depths, than B. gingivalis, and the total cell numbers of the two Bacteroides species was considerably more pronounced than the increase of the total subgingival plaque cell number with advancing probing depth.
134
Application of the Zürich biofilm model to problems of cariology.
TL;DR: A biofilm model developed in Zürich is described and a number of applications with direct or indirect impact on prophylactic dentistry are demonstrated: spatial arrangement and associative behavior of various species in biofilms; multiplex fluorescent in situ hybridization analysis of oral bacteria in biofilmms; use of the bio film model to predict in vivo efficacy of antimicrobials reliably.