Ruby Yun-Ju Huang
National Taiwan University
100 Papers
321 Citations
Ruby Yun-Ju Huang is an academic researcher from National Taiwan University. The author has contributed to research in topics: Cancer & Epithelial–mesenchymal transition. The author has an hindex of 33, co-authored 85 publications. Previous affiliations of Ruby Yun-Ju Huang include Agency for Science, Technology and Research & National University of Health Sciences.
Chat about Author
Papers
Epithelial-Mesenchymal Transitions in Development and Disease
Jean Paul Thiery,Jean Paul Thiery,Hervé Acloque,Ruby Yun-Ju Huang,Ruby Yun-Ju Huang,M. Angela Nieto +5 more
TL;DR: The mesenchymal state is associated with the capacity of cells to migrate to distant organs and maintain stemness, allowing their subsequent differentiation into multiple cell types during development and the initiation of metastasis.
9.9K
Guidelines and definitions for research on epithelial–mesenchymal transition
Jing Yang,Parker B. Antin,Geert Berx,Cédric Blanpain,Thomas Brabletz,Marianne E. Bronner,Kyra Campbell,Amparo Cano,Jordi Casanova,Gerhard Christofori,Shoukat Dedhar,Rik Derynck,Heide L. Ford,Jonas Fuxe,Antonio García de Herreros,Gregory J. Goodall,Anna-Katerina Hadjantonakis,Ruby Yun-Ju Huang,Chaya Kalcheim,Raghu Kalluri,Yibin Kang,Yeesim Khew-Goodall,Herbert Levine,Jinsong Liu,Gregory D. Longmore,Sendurai A. Mani,Joan Massagué,Roberto Mayor,David R. McClay,Keith E. Mostov,Donald F. Newgreen,M. Angela Nieto,Alain Puisieux,Alain Puisieux,Raymond B. Runyan,Pierre Savagner,Ben Z. Stanger,Marc P. Stemmler,Yoshiko Takahashi,Masatoshi Takeichi,Eric Theveneau,Jean Paul Thiery,Erik W. Thompson,Robert A. Weinberg,Elizabeth D. Williams,Jianhua Xing,Binhua P. Zhou,Guojun Sheng +47 more
TL;DR: This Consensus Statement is the outcome of a 2-year-long discussion among EMT researchers and aims to both clarify the nomenclature and provide definitions and guidelines for EMT research in future publications to reduce misunderstanding and misinterpretation of research data generated in various experimental models.
Epithelial-mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients.
Tuan Zea Tan,Qing Hao Miow,Yoshio Miki,Tetsuo Noda,Seiichi Mori,Ruby Yun-Ju Huang,Ruby Yun-Ju Huang,Jean Paul Thiery,Jean Paul Thiery +8 more
TL;DR: This universal and quantitative EMT scoring was used to establish an EMT spectrum across various cancers, with good correlation noted between cell lines and tumours, and it is demonstrated that mesenchymal‐like tumours do not always show resistance to chemotherapy.
802
Dual role of autophagy in hallmarks of cancer.
Shikha Satendra Singh,Somya Vats,Amelia Yi-Qian Chia,Tuan Zea Tan,Shuo Deng,Mei Shan Ong,Frank Arfuso,Celestial T. Yap,Boon Cher Goh,Gautam Sethi,Gautam Sethi,Ruby Yun-Ju Huang,Ruby Yun-Ju Huang,Han-Ming Shen,Ravi Manjithaya,Alan Prem Kumar +15 more
TL;DR: This review will provide a novel insight into the mutational landscapes of autophagy-related genes in several human cancers, using genetic information collected from an array of cancers.
504
Early events in cell adhesion and polarity during epithelial-mesenchymal transition
TL;DR: During evolution from primitive species, a mechanism was established to create mesenchymal cells from a pre-existing epithelial cell layer, but the direct and full conversion from an epithelial to a mesenchmonal state is not observed in all species.