Ross M. Tanis
University of South Carolina
6 Papers
51 Citations
Ross M. Tanis is an academic researcher from University of South Carolina. The author has contributed to research in topics: Unfolded protein response & Adipocyte. The author has an hindex of 5, co-authored 5 publications.
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Papers
Identification of protein succination as a novel modification of tubulin.
Gerardo G. Piroli,Allison M. Manuel,Michael D. Walla,Matthew J. Jepson,Jonathan W. C. Brock,Mathur Rajesh,Ross M. Tanis,William E. Cotham,Norma Frizzell +8 more
TL;DR: The results demonstrate that succination is a novel post-translational modification of tubulin and suggest that extensive modification by fumarate, either physiologically or pharmacologically, may alter microtubule dynamics.
Succination of Protein Disulfide Isomerase Links Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes
Allison M. Manuel,Michael D. Walla,Adam Faccenda,Stephanie L. Martin,Ross M. Tanis,Gerardo G. Piroli,Julie Adam,Boris Kantor,Bulent Mutus,Danyelle M. Townsend,Norma Frizzell +10 more
TL;DR: PDI succination is identified as a novel biochemical mechanism linking altered mitochondrial metabolism to ER stress in the adipocyte during diabetes, demonstrating the importance of calorie restriction in the improvement of adipocyte metabolic function.
Fumarate and oxidative stress synergize to promote stability of C/EBP homologous protein in the adipocyte
Allison M. Manuel,Michael D. Walla,Margaret T. Dorn,Ross M. Tanis,Gerardo G. Piroli,Norma Frizzell +5 more
TL;DR: In this article, the authors investigated the factors contributing to sustained CHOP proteins levels in the adipocyte, with an emphasis on the regulation of CHOP protein turnover by metabolite-driven modification of Keap1 cysteines.
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Comparison of Rhinitis Phenotypes with the Development of Asthma by Age 10 in an Urban Birth Cohort
Ross M. Tanis,Agustin Calatroni,Leonard B. Bacharier,F. Little,Megan Sandel,Katherine Rivera-Spoljaric,Cynthia M. Visness,Alkis Togias,Peter J. Gergen,James E. Gern,Sima K. Ramratnam,Carin I. Lamm,Robert J. Wood,Molly Jane Johnson +13 more
TL;DR: In this article , the authors examined the association between longitudinal patterns of childhood rhinitis and diagnosis of asthma in an urban birth cohort, and found that the relationship between allergic rashes and asthma is well established.
Ciliary gene RPGRIP1L is required for hypothalamic arcuate neuron development
Liheng Wang,Alain J. De Solis,Yossef Goffer,Kathryn E. Birkenbach,Staci E. Engle,Ross M. Tanis,Jacob M. Levenson,Xueting Li,Richard Rausch,Manika Purohit,Jen-Yi Lee,Jerica Tan,Maria Caterina De Rosa,Claudia A. Doege,Holly L. Aaron,Gabriela J. Martins,Jens C. Brüning,Dieter Egli,Rui M. Costa,Nicolas F. Berbari,Rudolph L. Leibel,George Stratigopoulos +21 more
TL;DR: It is suggested that apparently functional intronic polymorphisms affect hypothalamic RPGRIP1L expression and impact development of POMC neurons and their derivatives, leading to hyperphagia and increased adiposity.