Ronan Lyne
Trinity College, Dublin
4 Papers
Ronan Lyne is an academic researcher from Trinity College, Dublin. The author has contributed to research in topics: Expression quantitative trait loci & Schizophrenia (object-oriented programming). The author has an hindex of 3, co-authored 4 publications.
Chat about Author
Papers
BDNF-stimulated intracellular signalling mechanisms underlie exercise-induced improvement in spatial memory in the male Wistar rat
TL;DR: It is concluded that exercise-induced increases in BDNF in the dentate gyrus are sufficient to cause improvements in spatial memory by activating signalling cascades that enhance synaptic transmission in the hippocampus.
71
Convergent lines of evidence support CAMKK2 as a schizophrenia susceptibility gene
Xiong-Jian Luo,Ming Li,Liang Huang,Stacy Steinberg,Manuel Mattheisen,G. Liang,Gary Donohoe,Yongyong Shi,Chuansheng Chen,Weihua Yue,Anna Alkelai,B. Lerer,Zhiqiang Li,Q. Yi,Marcella Rietschel,Sven Cichon,D. A. Collier,Sarah Tosato,Jaana Suvisaari,Dan Rujescu,Vera Golimbet,Teimuraz Silagadze,Naser Durmishi,M. P. Milovancevic,Hreinn Stefansson,Thomas G. Schulze,Markus M. Nöthen,Ronan Lyne,Derek W. Morris,Michael Gill,Aiden Corvin,Dai Zhang,Qi Dong,Robert K. Moyzis,Kari Stefansson,Engilbert Sigurdsson,F. Hu,Bing Su,Lin Gan +38 more
TL;DR: Analysis of large-scale genome-wide expression studies revealed that CAMKK2 participates in a highly interconnected PPI network formed by top schizophrenia genes, which further supports the potential role of CAMKK 2 in the pathogenesis of schizophrenia.
Effects of MIR137 on fronto-amygdala functional connectivity
Omar Mothersill,Derek W. Morris,Sinead Kelly,Emma J. Rose,Emma J. Rose,Ciara Fahey,Carol O'Brien,Ronan Lyne,Richard B. Reilly,Michael Gill,Aiden Corvin,Gary Donohoe,Gary Donohoe +12 more
TL;DR: These findings provide the first evidence that the rs1625579 variant affects fronto-amygdala functional connectivity, providing further evidence that MIR137 may contribute to forms of psychosis in which affective symptoms are more prominent.
49
Convergent lines of evidence support CAMKK2 as a schizophrenia susceptibility gene
X-j Luo,Ming Li,Liang Huang,Stacy Steinberg,Manuel Mattheisen,G. Liang,Gary Donohoe,Yongyong Shi,Chuansheng Chen,Weihua Yue,Anna Alkelai,B. Lerer,Zhiqiang Li,Q. Yi,M. Rietschel,Sven Cichon,D. A. Collier,S. Tosato,Jaana Suvisaari,Dan Rujescu,Vera Golimbet,Teimuraz Silagadze,Naser Durmishi,M. P. Milovancevic,Hreinn Stefansson,Thomas G. Schulze,Markus M. Noethen,Ronan Lyne,Derek W. Morris,Michael Gill,Aiden Corvin,Dai Zhang,Qi Dong,Robert K. Moyzis,K. Stefansson,Engilbert Sigurdsson,F. Hu,Bing Su,Lin Gan +38 more
- 28 Aug 2014
TL;DR: Zhang et al. as discussed by the authors investigated the association between single-nucleotide polymorphisms (SNPs) within CAMKK2 and the expression level of CAMKK 2 in individuals with schizophrenia.