Ron A. M. Fouchier
Erasmus University Rotterdam
550 Papers
4.1K Citations
Ron A. M. Fouchier is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Virus & Influenza A virus. The author has an hindex of 111, co-authored 500 publications. Previous affiliations of Ron A. M. Fouchier include Crips & University of Amsterdam.
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Papers
Functional profile of human influenza virus-specific cytotoxic T lymphocyte activity is influenced by interleukin- 2 concentration and epitope specificity
TL;DR: The ability of influenza A virus‐specific cytotoxic T lymphocytes (CTL) to degranulate and produce cytokines upon antigenic restimulation was studied in four HLA•A*0101 and HLA‐A*0201 positive subjects.
Low-pH-induced membrane fusion mediated by human metapneumovirus F protein is a rare, strain-dependent phenomenon.
Sander Herfst,Vicente Mas,Lorena S. Ver,Rutger J. Wierda,Albert D. M. E. Osterhaus,Ron A. M. Fouchier,José A. Melero +6 more
TL;DR: Using prototype F proteins representing the four HMPV genetic lineages, it is found that low-pH-dependent fusion only with some lineage A proteins and not with lineage B proteins, and acidic pH is not a general trigger of H MPV F proteins for activity.
Residues of the Human Metapneumovirus Fusion (F) Protein Critical for Its Strain-Related Fusion Phenotype: Implications for the Virus Replication Cycle
TL;DR: Mutational analysis identifies four variable residues (294, 296, 396, and 404) as the main determinants of the different syncytial phenotypes found among hMPV F proteins that require low pH for cell-cell fusion.
Asymptomatic Middle East Respiratory Syndrome Coronavirus Infection in Rabbits
Bart L. Haagmans,Judith M. A. van den Brand,Lisette B. Provacia,V. Stalin Raj,Koert J. Stittelaar,Sarah Getu,Leon de Waal,Theo M. Bestebroer,Geert van Amerongen,Georges M. G. M. Verjans,Ron A. M. Fouchier,Saskia L. Smits,Thijs Kuiken,Albert D. M. E. Osterhaus +13 more
TL;DR: The ability of Middle East respiratory syndrome coronavirus (MERS-CoV) to infect small animal species may be restricted given the fact that mice, ferrets, and hamsters were shown to resist MERS- CoV infection.
Avian influenza virus: of virus and bird ecology.
TL;DR: An update on the current knowledge on the relation between host and virus ecology of LPAI in wild migratory birds is provided.