Romy Steiner
Medical University of Vienna
11 Papers
4 Citations
Romy Steiner is an academic researcher from Medical University of Vienna. The author has contributed to research in topics: Transplantation & Medicine. The author has an hindex of 1, co-authored 4 publications.
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Papers
Treg Therapy for the Induction of Immune Tolerance in Transplantation—Not Lost in Translation?
TL;DR: The results of the first Treg-based clinical trials seem promising, proving the feasibility and safety of Treg therapy in clinical organ transplantation as mentioned in this paper , however, many questions regarding Treg phenotype, optimum dosage, antigen-specificity, adjunct immunosuppressants and efficacy remain open.
Distinct roles for major and minor antigen barriers in chimerism‐based tolerance under irradiation‐free conditions
Benedikt Mahr,Nina Pilat,Nicolas Granofszky,Moritz Muckenhuber,Lukas Unger,Anna M. Weijler,Mario Wiletel,Romy Steiner,Lisa Dorner,Heinz Regele,Thomas Wekerle +10 more
TL;DR: It is concluded that under CB and rapamycin, MHC disparities provoke NK cell‐mediated BM rejection in nonirradiated recipients whereas MiHA disparities do not prevent BM engraftment but impede skin graft tolerance in established mixed chimeras.
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Adoptive transfer of allergen-expressing B cells prevents IgE-mediated allergy
Lisa Prickler,U. Baranyi,Konstantinos Mengrelis,A. Weijler,Verena Kainz,Bernhard Kratzer,Romy Steiner,Jasmin Mucha,Elisa Rudoph,Nina Pilat,Barbara Bohle,Herbert Strobl,Winfried F. Pickl,Rudolf Valenta,Birgit Linhart,Thomas Wekerle +15 more
TL;DR: It is demonstrated that the transfer of Phl p 5-expressing CD19+ B cells induces allergen-specific tolerance in a mouse model of grass pollen allergy and could be further translated into a prophylactic regimen for the prevention of IgE-mediated allergy in humans.
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T- and B-cell therapy in solid organ transplantation: current evidence and future expectations.
Nina Pilat,Katia Lefsihane,Sophie Brouard,Katja Kotsch,Christine S. Falk,Romy Steiner,Olivier Thaunat,Olivier Thaunat,Floriane Fusil,Nuria Montserrat,Nuria Montserrat,Cristiano Amarelli,Federica Casiraghi +12 more
TL;DR: In this article, the authors summarized available literature on cell-based innovative therapeutic approaches aiming at modulating allo-immune response for transplantation and highlighted the critical areas of investigation that need a joined effort of the transplant community for moving the field toward successful achievement of tolerance.
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Increased Nitrate Intake From Beetroot Juice Over 4 Weeks Changes the Composition of the Oral, But Not the Intestinal Microbiome.
Rebeka Fejes,Joana Séneca,Petra Pjevac,Martin Lutnik,Stefan Weisshaar,Nina Pilat,Romy Steiner,Karl-Heinz Wagner,Richard J. Woodman,Catherine P. Bondonno,Jonathan M. Hodgson,David Berry,Michael Wolzt,Oliver Neubauer +13 more
TL;DR: This randomized trial found that 4 weeks of beetroot juice consumption increased nitrate intake, altering the oral microbiome in older adults with hypertension, but had no effect on the intestinal microbiome, suggesting a selective modulation of the oral microbiome.