Romain Villot
Laval University
10 Papers
22 Citations
Romain Villot is an academic researcher from Laval University. The author has contributed to research in topics: DEPTOR & mTORC2. The author has an hindex of 4, co-authored 6 publications.
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Papers
Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity
Alexandre Caron,Sébastien M. Labbé,Damien Lanfray,Pierre-Gilles Blanchard,Romain Villot,Christian Roy,Denis Richard,Mathieu Laplante,David M. Sabatini +8 more
- 01 Dec 2015
TL;DR: A role for MBH DEPTOR in the regulation of energy balance and metabolism is supported by a novel conditional transgenic mouse model based on the Cre-LoxP system allowing targeted overexpression of DEPTor.
24
An inventory of crosstalk between ubiquitination and other post-translational modifications in orchestrating cellular processes
Haithem Barbour,Nadine Sen Nkwe,Benjamin Estavoyer,Clémence Messmer,Mila Gushul-Leclaire,Romain Villot,Maxime Uriarte,Karine Boulay,Sari Hlayhel,Bassel Farhat,Eric Milot,Frédérick A. Mallette,Salima Daou,El Bachir Affar +13 more
TL;DR: In this paper , the authors provide an extensive inventory of ubiquitination crosstalk with multiple PTMs including SUMOylation, phosphorylation, methylation, acetylation and hydroxylation.
23
Loss of hepatic DEPTOR alters the metabolic transition to fasting
Alexandre Caron,Mathilde Mouchiroud,Nicolas Gautier,Sébastien M. Labbé,Romain Villot,Laurie Turcotte,Blandine Secco,Lamoureux G,Michael Shum,Yves Gélinas,André Marette,Denis Richard,Mathieu Laplante,David M. Sabatini +13 more
- 01 May 2017
22
FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair
E Pinedo-Carpio,Julien Dessapt,Adèle Beneyton,Lauralicia Sacre,Marie-Anne Bérubé,Romain Villot,Elise G. Lavoie,Yannick Coulombe,Andréanne Blondeau,Jonathan Boulais,Abba Malina,Vincent M. Luo,Anna-Maria Lazaratos,Jean-François Côté,Frédérick A. Mallette,Alba Guarné,Jean-Yves Masson,Amélie Fradet-Turcotte,Alexandre Orthwein +18 more
TL;DR: It is shown that FIRRM, like its interactor Fidgetin like 1 (FIGNL1), contributes to the resolution of RAD51 foci at ICL-induced DSBs, establishing FIRRM as a promoting factor of ICL repair.
8
Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity.
Alexandre Caron,Sébastien M. Labbé,Damien Lanfray,Pierre-Gilles Blanchard,Romain Villot,Christian Roy,David M. Sabatini,Denis Richard,Mathieu Laplante +8 more
TL;DR: In this article, a DEP-domain containing mTOR-interacting protein (DEPTOR) was found to have a functional role in regulating energy balance and hypothalamic insulin signaling.