Rolf Bech Kjeldsen
Technical University of Denmark
7 Papers
Rolf Bech Kjeldsen is an academic researcher from Technical University of Denmark. The author has contributed to research in topics: Medicine & Drug delivery. The author has an hindex of 1, co-authored 2 publications.
Chat about Author
Papers
Management of oral biofilms by nisin delivery in adhesive microdevices.
Stine Egebro Birk,Mette Dalskov Mosgaard,Rolf Bech Kjeldsen,Anja Boisen,Rikke Louise Meyer,Line Hagner Nielsen +5 more
TL;DR: In this article, the authors investigated the potential of using miniaturized drug delivery devices, known as microcontainers (MCs), to deliver the antimicrobial peptide, nisin to an oral multi-species biofilm.
10
3D‐Printed Radiopaque Microdevices with Enhanced Mucoadhesive Geometry for Oral Drug Delivery
Tien-Jen Chang,Rolf Bech Kjeldsen,Juliane Fjelrad Christfort,Eduard Marzo i Vila,Tommy Sonne Alstrøm,Kinga Zor,En T. Hwu,Line Hagner Nielsen,Anja Boisen +8 more
TL;DR: In this article , the effect of 3D microdevice modifications on gastrointestinal retention is traced in vivo, and the applied methods provide a much-needed approach for investigating the impact of device design on gastrointestinal retraction.
7
Oral vaccination using microdevices to deliver α-GalCer adjuvanted vaccine afford mucosal immunity.
Philip H R Carlsen,Rolf Bech Kjeldsen,Gabriel K. Pedersen,Dennis Christensen,Line Hagner Nielsen,Anja Boisen +5 more
TL;DR: In this paper , the authors used MCs for oral delivery of C. trachomatis vaccine candidate CTH522, in combination with effective mucosal adjuvants such as alpha- galactosylceramide (α-GalCer), C-di-GMP and cholera toxin B.
5
A self-unfolding proximity enabling device for oral delivery of macromolecules.
Mahdi Ghavami,Jesper Pedersen,Rolf Bech Kjeldsen,Aage Kristian Olsen Alstrup,Zhongyang Zhang,Vasiliki Koulianou,Johan Palmfeldt,Thomas Vorup-Jensen,Lasse Højlund Thamdrup,Anja Boisen +9 more
TL;DR: A new generation of medical devices called self-unfolding proximity enabling devices are developed, which makes it possible to orally deliver macromolecules without perforating the intestine, and can facilitate enhanced absorption of minimally invasive oral Macromolecule formulations.
X-ray Imaging for Gastrointestinal Tracking of Microscale Oral Drug Delivery Devices.
Rolf Bech Kjeldsen,Maja Nørgaard Kristensen,Maja Nørgaard Kristensen,Carsten Gundlach,Lasse Højlund Thamdrup,Anette Müllertz,Anette Müllertz,Thomas Rades,Thomas Rades,Line Hagner Nielsen,Kinga Zor,Anja Boisen +11 more
TL;DR: In this article, the authors used planar X-ray imaging and computed tomography (CT) scanning for visualization and tracking of micro-scale devices in the GI tract of rats.