Roland H. Stote
French Institute of Health and Medical Research
59 Papers
626 Citations
Roland H. Stote is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Allosteric regulation & Protein structure. The author has an hindex of 25, co-authored 57 publications. Previous affiliations of Roland H. Stote include Harvard University & University of Strasbourg.
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Papers
All-atom empirical potential for molecular modeling and dynamics studies of proteins.
Alexander D. MacKerell,D. Bashford,M. Bellott,Roland L. Dunbrack,Jeffrey D. Evanseck,Martin J. Field,Stefan Fischer,Jiali Gao,H. Guo,S. Ha,Diane Joseph-McCarthy,L. Kuchnir,K. Kuczera,F. T. K. Lau,C. Mattos,Stephen W. Michnick,Thien H. Ngo,D. T. Nguyen,B. Prodhom,W. E. Reiher,Benoît Roux,M. Schlenkrich,Jeremy C. Smith,Roland H. Stote,John E. Straub,Masakatsu Watanabe,J. Wiórkiewicz-Kuczera,D. Yin,Martin Karplus +28 more
TL;DR: The results demonstrate that use of ab initio structural and energetic data by themselves are not sufficient to obtain an adequate backbone representation for peptides and proteins in solution and in crystals.
Zinc binding in proteins and solution: A simple but accurate nonbonded representation
Roland H. Stote,Martin Karplus +1 more
TL;DR: It is concluded that the present parameter set, which permits different coordination geometries and ligand exchange for the zinc ion, can be employed effectively for both solution and protein simulations of zinc‐containing systems.
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Allostery in Its Many Disguises: From Theory to Applications
Shoshana J. Wodak,Emanuele Paci,Nikolay V. Dokholyan,Nikolay V. Dokholyan,Igor N. Berezovsky,Amnon Horovitz,Jing Li,Vincent J. Hilser,Ivet Bahar,John Karanicolas,Gerhard Stock,Peter Hamm,Roland H. Stote,Jerome Eberhardt,Yassmine Chebaro,Annick Dejaegere,Marco Cecchini,Jean-Pierre Changeux,Peter G. Bolhuis,Jocelyne Vreede,Pietro Faccioli,Simone Orioli,Riccardo Ravasio,Le Yan,Carolina Brito,Matthieu Wyart,Paraskevi Gkeka,Ivan Rivalta,Giulia Palermo,Giulia Palermo,J. Andrew McCammon,Joanna Panecka-Hofman,Rebecca C. Wade,Rebecca C. Wade,Antonella Di Pizio,Masha Y. Niv,Ruth Nussinov,Chung-Jung Tsai,Hyunbum Jang,Dzmitry Padhorny,Dima Kozakov,Tom McLeish +41 more
TL;DR: An overview of the progress and remaining limitations in the understanding of the mechanistic foundations of allostery gained from computational and experimental analyses of real protein systems and model systems is provided.
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Structural basis for hijacking of cellular LxxLL motifs by papillomavirus E6 oncoproteins.
Katia Zanier,Sebastian Charbonnier,Abdellahi Ould M'hamed Ould Sidi,Alastair G. McEwen,Maria Giovanna Ferrario,Pierre Poussin-Courmontagne,V. Cura,Nicole Brimer,Khaled Ould Babah,Tina Ansari,Isabelle Muller,Roland H. Stote,Jean Cavarelli,Scott B. Vande Pol,Gilles Travé +14 more
TL;DR: The structural basis of both the multifunctionality and the oncogenicity of E6 proteins is revealed, including a basic-hydrophobic pocket, which captures helical LxxLL motifs in a way compatible with other interaction modes.
Oxidation of thymine to 5-formyluracil in DNA: mechanisms of formation, structural implications, and base excision by human cell free extracts.
Svein Bjelland,Lars Eide,Rune W. Time,Roland H. Stote,Ingrid Eftedal,Gunnar Volden,Erling Seeberg +6 more
TL;DR: It is shown that 5-foU residues are formed with high frequency from thymine by quinone-sensitized UV-A photooxidation by neutral thermal hydrolysis and reverse phase high-performance liquid chromatography to determine the content of the oxidation product 5-formyluracil (5-fo U) in DNA.
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