Rodrigo Benavides
McGill University
5 Papers
4 Citations
Rodrigo Benavides is an academic researcher from McGill University. The author has contributed to research in topics: Chronic pain & Traumatic brain injury. The author has an hindex of 3, co-authored 4 publications.
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Papers
Human pain genetics database: a resource dedicated to human pain genetics research.
Carolina B. Meloto,Rodrigo Benavides,Ryan N. Lichtenwalter,Xia Wen,Nicol Tugarinov,Katerina Zorina-Lichtenwalter,Anne-Julie Chabot-Doré,Marjo Piltonen,Stefano Cattaneo,Vivek Verma,Richard Klares,Samar Khoury,Marc Parisien,Luda Diatchenko +13 more
TL;DR: It is demonstrated that the HPGDB data set is significantly enriched for functional variants that modify gene expression, are deleterious, and colocalize with open chromatin regions, indicating that genetic pathophysiological mechanisms are also shared among painful and nonpainful conditions.
72
Pain with traumatic brain injury and psychological disorders
Samar Khoury,Rodrigo Benavides +1 more
TL;DR: The most commonly reported chronic pain conditions across the spectrum of severity of TBI, mainly focusing on mild TBI are presented and general aspects of management of chronic pain post‐TBI are addressed.
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A functional polymorphism in the ATP-Binding Cassette B1 transporter predicts pharmacologic response to combination of nortriptyline and morphine in neuropathic pain patients.
Rodrigo Benavides,Olga A. Vsevolozhskaya,Stefano Cattaneo,Dmitri V. Zaykin,Ashley Brenton,Marc Parisien,Vivek Verma,Samar Khoury,Ian Gilron,Luda Diatchenko +9 more
TL;DR: A robust effect of the rs1045642 polymorphism on response to chronic pain treatment with a nortriptyline + morphine combination therapy is shown, suggesting better pain control.
20
Post-concussion symptoms and chronic pain after mild traumatic brain injury are modulated by multiple locus effect in the BDNF gene through the expression of antisense: A pilot prospective control study
Samar Khoury,Julia Segal,Marc Parisien,Anne Noreau,Patrick A. Dion,Rodrigo Benavides,Jean-François Giguère,Ronald Denis,Inna Belfer,Luda Diatchenko,Guy A. Rouleau,Gilles Lavigne +11 more
- 04 Aug 2017
TL;DR: A protective mechanism of a multilocus effect in BDNF, through BDNF-AS, against post-concussion symptoms and pain in the acute phase and possibly chronic pain at one year post-mTBI is suggested.
4
A graph-embedded topic model enables characterization of diverse pain phenotypes among UK biobank individuals
TL;DR: In this paper , a graph embedded topic model (GETM) is proposed to predict and characterize chronic pain using latent phenotypes from self-reported clinical phenotype data from the UK Biobank.