Rodolfo Montironi
Marche Polytechnic University
1014 Papers
6.1K Citations
Rodolfo Montironi is an academic researcher from Marche Polytechnic University. The author has contributed to research in topics: Prostate cancer & Medicine. The author has an hindex of 83, co-authored 958 publications. Previous affiliations of Rodolfo Montironi include United Hospitals & Cordoba University.
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Papers
Understanding the mechanisms of androgen deprivation resistance in prostate cancer at the molecular level.
Theodoros Karantanos,Christopher P. Evans,Bertrand Tombal,Timothy C. Thompson,Rodolfo Montironi,William B. Isaacs +5 more
TL;DR: This review focuses on androgen biosynthesis in the tumor microenvironment, androgen receptor alterations and post-transcriptional modifications, the role of glucocorticoid receptor, and alternative oncogenic signaling that is derepressed on maximum AR inhibition and thus promotes cancer survival and progression.
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Metabolic phenotype of bladder cancer
Francesco Massari,Chiara Ciccarese,Matteo Santoni,Roberto Iacovelli,Roberta Mazzucchelli,Francesco Piva,Marina Scarpelli,Rossana Berardi,Giampaolo Tortora,Antonio Lopez-Beltran,Liang Cheng,Rodolfo Montironi +11 more
TL;DR: A deep understanding of the metabolic phenotype of bladder cancer will provide novel opportunities for targeted therapeutic strategies, as well as contribute to cancer metabolic switch and tumor cell proliferation.
282
Updated Results of PURE-01 with Preliminary Activity of Neoadjuvant Pembrolizumab in Patients with Muscle-invasive Bladder Carcinoma with Variant Histologies
Andrea Necchi,Daniele Raggi,Andrea Gallina,Russell Madison,Maurizio Colecchia,Roberta Lucianò,Rodolfo Montironi,Patrizia Giannatempo,Elena Farè,Filippo Pederzoli,Marco Bandini,Marco Bianchi,Renzo Colombo,Giorgio Gandaglia,Nicola Fossati,Laura Marandino,Umberto Capitanio,Federico Dehò,Siraj M. Ali,Jon Chung,Jeffrey S. Ross,Andrea Salonia,Alberto Briganti,Francesco Montorsi +23 more
TL;DR: The updated PURE-01 results confirm the activity of neoadjuvant pembrolizumab in MIBC and VH and provide a rationale for selecting patients according to these features instead of the histological bladder cancer subtypes.
281
Contemporary Role of Systematic Prostate Biopsies: Indications, Techniques, and Implications for Patient Care
Osamu Ukimura,Osamu Ukimura,Jonathan A. Coleman,Alex de la Taille,Mark Emberton,Mark Emberton,Jonathan I. Epstein,Stephen J. Freedland,Gianluca Giannarini,Adam S. Kibel,Rodolfo Montironi,Guillaume Ploussard,Monique J. Roobol,Vincenzo Scattoni,J. Stephen Jones +14 more
TL;DR: Current data support the utility of extended PB templates for initial TRUS PB intended to detect clinically significant PCa, and debate continues regarding indications, sampling number, and location as well as on the potential of modern image-guided approaches or three-dimensional mapping biopsy in this unique setting.
268
The 2004 WHO Classification of Bladder Tumors: A Summary and Commentary:
TL;DR: The key points of the latest World Health Organization classification of noninvasive urothelial tumors are the following: the description of the categories has been expanded to improve their recognition, and a tumor with particularly good prognosis no longer carries the label of ‘cancer’.
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