Robin Lüling
Ludwig Maximilian University of Munich
9 Papers
15 Citations
Robin Lüling is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Chemistry & Cysteine. The author has an hindex of 4, co-authored 9 publications.
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Papers
Alkylated epidermal creatine kinase as a biomarker for sulfur mustard exposure: comparison to adducts of albumin and DNA in an in vivo rat study.
Dirk Steinritz,Robin Lüling,Markus Siegert,Julia Herbert,Harald Mückter,Christian D. Taeger,Thomas Gudermann,Alexander Dietrich,Horst Thiermann,Harald John +9 more
TL;DR: In this paper, a novel biomarker, namely creatine kinase (CK) B-type, suitable as a local biomarker for sulfur mustard exposure on the skin was reported.
Identification of creatine kinase and alpha-1 antitrypsin as protein targets of alkylation by sulfur mustard.
Robin Lüling,Wolfgang Schmeißer,Markus Siegert,Harald Mückter,Alexander Dietrich,Horst Thiermann,Thomas Gudermann,Harald John,Dirk Steinritz +8 more
TL;DR: This is the first report introducing these endogenous proteins as targets of SM alkylation as being alkylated by SM bearing the specific hydroxyethylthioethyl-(HETE)-moiety.
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Transthyretin as a target of alkylation and a potential biomarker for sulfur mustard poisoning: electrophoretic and mass spectrometric identification and characterization.
TL;DR: In this paper, a 2D thiol difference gel electrophoresis (2D-thiol-DIGE) technique making use of maleimide dyes allows the staining of free cysteine residues in proteins.
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Sulfur mustard alkylates steroid hormones and impacts hormone function in vitro
Robin Lüling,Helena Singer,Tanja Popp,Harald John,Ingrid Boekhoff,Horst Thiermann,Lena J. Daumann,Konstantin Karaghiosoff,Thomas Gudermann,Dirk Steinritz +9 more
TL;DR: GCs are presented as new biological targets of SM associated with a disturbance of hormone function as well as biological function of SM-alkylated GCs investigated using GC-regulated dual-luciferase reporter gene assays.
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Immediate responses of the cockroach Blaptica dubia after the exposure to sulfur mustard.
Tanja Popp,Robin Lüling,Ingrid Boekhoff,Thomas Seeger,Francisco Branoner,Thomas Gudermann,Horst Thiermann,Franz Worek,Dirk Steinritz +8 more
TL;DR: Using the cockroach model Blaptica dubia, the presented results show that alkylating compounds provoke immediate behavior responses along with fast changes in the electrical field potential (EFP) of neurons, suggesting that lesions of DNA are probably not the only effect of alkyLating compounds.
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