This review summarizes evidence that has become available since the 2002 U.S. Preventive Services Task Force recommendations on osteoporosis screening to inform updated recommendations. No trials o...

/pdf/screening-for-osteoporosis-an-update-for-the-u-s-preventive-3rrnp7q2e8.pdf

Screening for osteoporosis: an update for the U.S. Preventive Services Task Force.

Body mass index is not a good predictor of bone density: results from WHI, CHS, and EPIDOS.

Screening for Osteoporosis: Systematic Review to Update the 2002 U.S. Preventive Services Task Force Recommendation

There is a need for a cost-effective method to identify individuals with a high risk of osteoporosis. This study aimed to investigate the suitability of hand grip strength in predicting the risk of osteoporosis in Asian adults. In this cross-sectional, hospital-based study of 1007 participants, the bone mineral density of the spine and hips was evaluated using dual-energy X-ray absorptiometry according to the 2019 International Society for Clinical Densitometry official positions. Bone microarchitecture was evaluated using the trabecular bone score, and hand grip strength was measured in the dominant hand using a hand digital dynamometer. Hand grip strength was significantly related to bone density and bone microarchitecture. Moreover, hand grip strength was a significant predictor of osteoporosis in both women and men. For osteoporosis prediction in women, a threshold of 21.9 kg of hand grip strength had a sensitivity of 59%, specificity of 59%, and area under the curve (AUC) of 0.61. In men, a threshold of 28.7 kg had a sensitivity of 66%, specificity of 78%, and AUC of 0.75. The optimal cutoff strengths for osteoporosis depended on age and sex. The measurement of hand grip strength is a simple, cost-effective and an easy assessment method for identifying individuals at a high risk of osteoporosis. The cutoff strength for evaluating osteoporosis in adults is age and sex specific.

Hand grip strength in predicting the risk of osteoporosis in Asian adults

The Osteoporosis Self-assessment Tool (OST) is a clinical instrument designed to select patients at risk of osteoporosis, who would benefit from a bone mineral density measurement. The OST only takes into account the age and weight of the subject. It was developed for Asian women and later validated for European and North American white women. The performance of the OST in a sample of 4343 women from Greater Mendoza, a large metropolitan area of Argentina, was assessed. Dual X-ray absorptiometry (DXA) scans of lumbar spine and hip were obtained. Patients were classified as either osteoporotic () or nonosteoporotic () according to their lowest T-score at any site. Osteoporotic patients had lower OST scores (). A receiver operating characteristic (ROC) curve showed an area under the curve of 71% (), with a sensitivity of 83.7% and a specificity of 44% for a cut-off value of 2. Positive predictive value was 52% and negative predictive value was 79%. The odds ratio for the diagnosis of osteoporosis was 4.06 (CI95 3.51 to 4.71; ). It is concluded that the OST is useful for selecting postmenopausal women for DXA testing in the studied population.

/pdf/osteoporosis-self-assessment-tool-performance-in-a-large-3pz5we7cmz.pdf

Osteoporosis Self-Assessment Tool Performance in a Large Sample of Postmenopausal Women of Mendoza, Argentina

Construction of two instruments for the presumptive detection of post-menopausal women with low spinal bone mass by means of clinical risk factors.

The impact of a monophasic continuous estro-progestogenic treatment on Latin American menopausal women.

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Construction of two instruments for the presumptive detection of post-menopausal women with low spinal bone mass by means of clinical risk factors.

The impact of a monophasic continuous estro-progestogenic treatment on Latin American menopausal women.