Roberto Tirabosco
Royal National Orthopaedic Hospital
125 Papers
251 Citations
Roberto Tirabosco is an academic researcher from Royal National Orthopaedic Hospital. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 42, co-authored 110 publications.
Chat about Author
Papers
A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma
Lisa Mirabello,Roelof Koster,Branden S. Moriarity,Logan G. Spector,Paul S. Meltzer,Joy Gary,Mitchell J. Machiela,Nathan Pankratz,Orestis A. Panagiotou,David A. Largaespada,Zhaoming Wang,Julie M. Gastier-Foster,Richard Gorlick,Chand Khanna,Silvia Regina Caminada de Toledo,Antonio Sergio Petrilli,Ana Patiño-García,Luis Sierrasesúmaga,Fernando Lecanda,Irene L. Andrulis,Jay S. Wunder,Nalan Gokgoz,Massimo Serra,Claudia Maria Hattinger,Piero Picci,Katia Scotlandi,Adrienne M. Flanagan,Adrienne M. Flanagan,Roberto Tirabosco,Maria Fernanda Amary,Dina Halai,Mandy L. Ballinger,David Thomas,Sean Davis,Donald A. Barkauskas,Neyssa Marina,Lee J. Helman,George Maxwell Otto,Kelsie L. Becklin,Natalie K. Wolf,Madison T. Weg,Margaret A. Tucker,Sholom Wacholder,Joseph F. Fraumeni,Neil E. Caporaso,Joseph Boland,Belynda Hicks,Aurelie Vogt,Laurie Burdett,Meredith Yeager,Robert N. Hoover,Stephen J. Chanock,Sharon A. Savage +52 more
TL;DR: Data show data that are supportive for the NFIB locus as associated with metastatic potential in osteosarcoma, and suggest that germline genetic variation at rs7034162 is important in bone malignancy and that NFIB is an osteosARcoma metastasis susceptibility gene.
GNAS1 mutations occur more commonly than previously thought in intramuscular myxoma.
David Delaney,Tim C. Diss,Nadege Presneau,Sandra Nalini Hing,Fitim Berisha,Bernadine Idowu,Paul O'Donnell,John A. Skinner,Roberto Tirabosco,Adrienne M. Flanagan +9 more
TL;DR: This study shows the power of COLD-PCR compared with conventional PCR in mutation detection, and shows that GNAS1 mutation detection increases diagnostic accuracy when distinguishing between intramuscular myxoma and low-grade myxofibrosarcoma.
MRI characteristics of lipoma and atypical lipomatous tumor/well-differentiated liposarcoma: retrospective comparison with histology and MDM2 gene amplification
Melanie Brisson,Takeshi Kashima,David Delaney,Roberto Tirabosco,Andrew W. Clarke,Suzie Cro,Adrienne M. Flanagan,Adrienne M. Flanagan,Paul O'Donnell,Paul O'Donnell +9 more
TL;DR: The most reliable imaging discriminators of ALT/WDL were size of lesion and lipomatous content, but due to the overlap in the MRI appearances of lipoma and ALT-WDL, discrimination should be based on molecular pathology rather than imaging.
Isocitrate dehydrogenase 1 mutations (IDH1) and p16/CDKN2A copy number change in conventional chondrosarcomas.
M Fernanda Amary,M Fernanda Amary,Hongtao Ye,Georgina Forbes,Stephen Damato,Francesca Maggiani,Robin Pollock,Roberto Tirabosco,Adrienne M. Flanagan,Adrienne M. Flanagan +9 more
TL;DR: The study shows that if an IDH1 mutation were detected in a primary central chondrosarcoma, it is always detected at the time of presentation, and the same mutation is detected in local recurrences and metastatic events, and p16/CDKN2A copy number variation is seen in both the IDH 1 wild-type and mutant cartilaginous central tumours.
PRDM10-rearranged Soft Tissue Tumor: A Clinicopathologic Study of 9 Cases.
Florian Puls,Nischalan Pillay,Henrik Fagman,Anne Palin-Masreliez,Fernanda Amary,Magnus Hansson,Lars-Gunnar Kindblom,Tom A. McCulloch,George Meligonis,Ronald Muc,Pehr Rissler,Vaiyapuri Sumathi,Roberto Tirabosco,Jakob Hofvander,Linda Magnusson,Jenny Nilsson,Adrienne M. Flanagan,Fredrik Mertens +17 more
TL;DR: Clinical features of this small series suggest an indolent behavior of PRDM10-rearranged soft tissue tumor, justifying its distinction from UPS and other sarcomas.