Roberto S. Accolla
University of Insubria
175 Papers
3.1K Citations
Roberto S. Accolla is an academic researcher from University of Insubria. The author has contributed to research in topics: CIITA & Antigen. The author has an hindex of 40, co-authored 163 publications. Previous affiliations of Roberto S. Accolla include Ludwig Institute for Cancer Research & Centre national de la recherche scientifique.
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Papers
Human interleukin-2 promotes proliferation of activated B cells via surface receptors similar to those of activated T cells
Maria Cristina Mingari,F. Gerosa,G. Carra,Roberto S. Accolla,Alessandro Moretta,R. H. Zubler,T. A. Waldmann,Lorenzo Moretta +7 more
TL;DR: It is shown that recombinant IL-2, derived from Escherichia coli expressing the human gene8, is able to promote strong proliferation of human B cells activated with protein-A-rich Staphylococcus aureus Cowans strain I2.
383
•Journal Article
Common human melanoma-associated antigen(s) detected by monoclonal antibodies.
TL;DR: Reciprocal binding inhibition tests using [3H]leeucine-labeled antibodies showed that alpha-Mel/5 and alpha- Mel/14 antibodies were directed against different antigenic determinants.
212
Human B cell variants immunoselected against a single Ia antigen subset have lost expression of several Ia antigen subsets.
TL;DR: Results showed that, irrespective of the monoclonal antibody used for immunoselection, the cell variants analyzed in this study had lost the expression of both D1-12-and BT 2.2-specific antigenic determinants.
Monoclonal antibodies specific for carcinoembryonic antigen and produced by two hybrid cell lines
TL;DR: Spleen cells from mice immunized with purified carcinoembryonic antigen, an important tumor marker of human carcinomas, were fused with the mouse myeloma cell line P3-NSI/1-Ag4 and 2 secreted antibodies reacting specifically with two different antigenic determinants present on CEA molecules were obtained.
162
Subsets of human Ia-like molecules defined by monoclonal antibodies.
Stefan Carrel,Roberto Tosi,Nicole Gross,Noboyuki Tanigaki,Anna L. Carmagnola,Roberto S. Accolla +5 more
TL;DR: Two human Ia molecule subsets were denned by their activity with hybridoma antibodies raised against Daudi cell membranes, and appear to carry alternative forms of this subunit.
148