Roberta Corti
University of Milano-Bicocca
10 Papers
14 Citations
Roberta Corti is an academic researcher from University of Milano-Bicocca. The author has contributed to research in topics: Extracellular matrix & Magnetic tweezers. The author has an hindex of 4, co-authored 10 publications. Previous affiliations of Roberta Corti include University of Milan.
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Papers
The Extent of Human Apolipoprotein A-I Lipidation Strongly Affects the β-Amyloid Efflux Across the Blood-Brain Barrier in vitro.
Roberta Dal Magro,Sara Simonelli,Alysia Cox,Beatrice Formicola,Roberta Corti,Valeria Cassina,Luca Nardo,Francesco Mantegazza,Domenico Salerno,Gianvito Grasso,Marco Agostino Deriu,Andrea Danani,Laura Calabresi,Francesca Re +13 more
TL;DR: The results showed that discoidal HDL displayed a superior capability to promote Aβ efflux in vitro, when compared to apoA-I in other lipidation states, suggesting that apo-I conformation, and lipidation could play a role in Aβ clearance from the brain.
Major Action of Endogenous Lysyl Oxidase in Clear Cell Renal Cell Carcinoma Progression and Collagen Stiffness Revealed by Primary Cell Cultures.
Vitalba Di Stefano,Barbara Torsello,Cristina Bianchi,Ingrid Cifola,Eleonora Mangano,Giorgio Bovo,Valeria Cassina,Sofia De Marco,Roberta Corti,C Meregalli,Silvia Bombelli,P Viganò,Cristina Battaglia,Cristina Battaglia,Guido Strada,Roberto A. Perego +15 more
TL;DR: It is found that endogenous LOX is overexpressed in ccRCC, is involved in a positive-regulative loop with HIF-1α, and has a major action onccRCC progression through cellular adhesion, migration, and collagen matrix stiffness increment; however, the oncosuppressive action of Lox-PP was not found to prevail.
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ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine.
Diletta Fontana,Mario Mauri,Rossella Renso,Mattia Docci,Ilaria Crespiatico,Lisa Marie Røst,Mi Jang,Antonio Niro,Deborah D'Aliberti,Luca Massimino,Mayla Bertagna,Giovanni Zambrotta,M Bossi,Stefania Citterio,Barbara Crescenzi,Francesca Fanelli,Valeria Cassina,Roberta Corti,Domenico Salerno,Luca Nardo,Clizia Chinello,Francesco Mantegazza,Cristina Mecucci,Fulvio Magni,Guido Cavaletti,Per Bruheim,Delphine Rea,Steen Larsen,Steen Larsen,Carlo Gambacorti-Passerini,Rocco Piazza +30 more
TL;DR: It is demonstrated in primary leukemic cells and in cell lines that mutated ETNK1 causes a significant increase in mitochondrial activity, ROS production, and Histone H2AX phosphorylation, ultimately driving the increased accumulation of new mutations.
Nanomechanics of Diaminopurine-Substituted DNA.
Matteo Cristofalo,Daniel T. Kovari,Roberta Corti,Domenico Salerno,Valeria Cassina,David Dunlap,Francesco Mantegazza +6 more
TL;DR: It is demonstrated that in addition to stabilizing double-strand hybridization, DAP substitution also changes the mechanical and conformational properties of dsDNA, which increases the flexural rigidity of dAP yet also facilitates conformational shifts, which manifest as changes in molecule length.
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Depicting Conformational Ensembles of α-Synuclein by Single Molecule Force Spectroscopy and Native Mass Spectroscopy.
Roberta Corti,Claudia Adriana Marrano,Domenico Salerno,Stefania Brocca,Antonino Natalello,Carlo Santambrogio,Giuseppe Legname,Francesco Mantegazza,Rita Grandori,Cassina +9 more
TL;DR: This comparative analysis provides support to structural interpretation of charge-state distributions obtained by native mass spectrometry and helps, in turn, defining the conformational components detected by single molecule force spectroscopy.
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