Robert W. Prosser

TL;DR: Using human mitochondrial replacement stem cell lines, it is shown that, even though the low levels of heteroplasmy introduced into human oocytes by mitochondrial carryover during nuclear transfer often vanish, they can sometimes instead result in mtDNA genotypic drift and reversion to the original genotype.

TL;DR: Studies of luteinizing hormone (LH)-mediated serum inhibition and of follicular fluid and granulosa cell inhibition of in vitro porcine, ewe, and cow oocyte meiotic maturation have been carried out and it is postulated that the follicular fluids inhibitor may be derived from the larger serum molecule by an action of LH within an intermediate cell type.

TL;DR: While ICSI does not need to be categorically instituted when using donor spermatozoa in IVF, patients should be counseled that conversion from insemination to I CSI may be recommended based on low post-processing motility.

TL;DR: The addition of NETA does not attenuate COH in women undergoing IVF, and no differences were noted in days of stimulation, peak estradiol (E2) level attained, peak E2-to-oocyte ratio, dosage of exogenous gonadotropins, number of aspirated oocytes, fertilization rate, or oocyte and preembryo quality.